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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRF1
All Species:
25.15
Human Site:
Y53
Identified Species:
61.48
UniProt:
Q13972
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13972
NP_722522.1
1275
145383
Y53
L
L
Q
N
L
L
F
Y
F
E
S
D
S
S
S
Chimpanzee
Pan troglodytes
XP_001153586
1273
145146
Y53
L
L
Q
N
L
L
F
Y
F
E
S
D
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001108408
514
59608
Dog
Lupus familis
XP_545892
1304
148017
Y53
L
L
Q
N
L
L
F
Y
F
E
S
D
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P27671
1262
144083
Y53
L
L
Q
N
L
L
F
Y
F
E
S
D
S
S
P
Rat
Rattus norvegicus
P28818
1244
142649
Y53
L
L
Q
N
L
L
F
Y
F
E
S
D
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510010
1242
141041
Y53
L
Y
Q
N
V
L
F
Y
F
E
G
E
Q
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEA7
1244
141569
Y53
L
Y
Q
N
V
L
F
Y
F
D
T
D
Q
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122143
690
76494
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780300
1211
137984
W39
K
S
S
D
T
G
K
W
K
Q
R
W
C
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
39.6
93.3
N.A.
83.4
83.1
N.A.
64.8
N.A.
N.A.
65.3
N.A.
N.A.
25.1
N.A.
48
Protein Similarity:
100
99.4
39.9
94.9
N.A.
90.3
90.3
N.A.
78.7
N.A.
N.A.
78.4
N.A.
N.A.
36.3
N.A.
65.5
P-Site Identity:
100
100
0
100
N.A.
93.3
100
N.A.
60
N.A.
N.A.
60
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
0
100
N.A.
93.3
100
N.A.
73.3
N.A.
N.A.
86.6
N.A.
N.A.
0
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
10
0
60
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
60
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
70
0
70
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% K
% Leu:
70
50
0
0
50
70
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
70
0
0
0
0
0
0
10
0
0
20
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
10
10
0
0
0
0
0
0
0
50
0
50
70
40
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% W
% Tyr:
0
20
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _