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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRF1
All Species:
1.21
Human Site:
Y925
Identified Species:
2.96
UniProt:
Q13972
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13972
NP_722522.1
1275
145383
Y925
G
T
P
N
K
E
K
Y
R
R
M
S
L
A
S
Chimpanzee
Pan troglodytes
XP_001153586
1273
145146
R925
P
N
K
E
K
Y
R
R
M
S
L
A
S
A
G
Rhesus Macaque
Macaca mulatta
XP_001108408
514
59608
S190
K
D
N
E
R
I
Q
S
T
Q
T
V
A
P
N
Dog
Lupus familis
XP_545892
1304
148017
D918
A
S
T
G
F
P
P
D
Q
R
N
G
D
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P27671
1262
144083
Q926
N
T
G
F
S
S
D
Q
R
N
I
D
K
E
F
Rat
Rattus norvegicus
P28818
1244
142649
N910
G
Y
S
S
D
Q
R
N
I
D
K
E
F
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510010
1242
141041
R917
D
K
E
F
I
I
R
R
T
A
T
N
R
V
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEA7
1244
141569
E908
P
P
V
F
N
N
S
E
R
T
C
D
K
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122143
690
76494
K366
T
V
L
E
A
L
K
K
V
F
Y
E
A
E
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780300
1211
137984
A881
N
M
L
S
R
K
R
A
K
K
S
Y
G
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
39.6
93.3
N.A.
83.4
83.1
N.A.
64.8
N.A.
N.A.
65.3
N.A.
N.A.
25.1
N.A.
48
Protein Similarity:
100
99.4
39.9
94.9
N.A.
90.3
90.3
N.A.
78.7
N.A.
N.A.
78.4
N.A.
N.A.
36.3
N.A.
65.5
P-Site Identity:
100
13.3
0
6.6
N.A.
13.3
6.6
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
33.3
26.6
20
N.A.
20
26.6
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
6.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
10
0
10
0
10
20
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
10
0
0
10
0
10
10
0
10
0
20
10
0
0
% D
% Glu:
0
0
10
30
0
10
0
10
0
0
0
20
0
30
10
% E
% Phe:
0
0
0
30
10
0
0
0
0
10
0
0
10
0
20
% F
% Gly:
20
0
10
10
0
0
0
0
0
0
0
10
10
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
20
0
0
10
0
10
0
0
0
10
% I
% Lys:
10
10
10
0
20
10
20
10
10
10
10
0
20
10
0
% K
% Leu:
0
0
20
0
0
10
0
0
0
0
10
0
10
0
10
% L
% Met:
0
10
0
0
0
0
0
0
10
0
10
0
0
0
0
% M
% Asn:
20
10
10
10
10
10
0
10
0
10
10
10
0
0
10
% N
% Pro:
20
10
10
0
0
10
10
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
10
10
10
10
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
20
0
40
20
30
20
0
0
10
10
0
% R
% Ser:
0
10
10
20
10
10
10
10
0
10
10
10
10
0
10
% S
% Thr:
10
20
10
0
0
0
0
0
20
10
20
0
0
0
0
% T
% Val:
0
10
10
0
0
0
0
0
10
0
0
10
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
10
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _