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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CIRBP All Species: 20.91
Human Site: S130 Identified Species: 41.82
UniProt: Q14011 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14011 NP_001271.1 172 18648 S130 Y G G N R F E S R S G G Y G G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094149 200 21970 S130 Y G G N R F E S R S G G Y G G
Dog Lupus familis XP_868602 219 23193 S177 Y G G S R F E S R S G G Y G G
Cat Felis silvestris
Mouse Mus musculus O89086 153 16586 S112 G G D Q G Y G S G R Y D S R P
Rat Rattus norvegicus Q925G0 155 16836 Y112 R G G G D Q G Y G S G R Y D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512332 172 18632 S130 Y G G S R F E S R S G G Y G G
Chicken Gallus gallus NP_001026518 190 20955 S130 Y G G S R F D S R S G G Y N G
Frog Xenopus laevis Q9DED4 166 17837 S125 S S R F D N R S G G Y G G S S
Zebra Danio Brachydanio rerio NP_956311 184 19185 G133 F G G D R S Y G G D R S Y G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48809 421 44751 A341 D M Y S R A Q A W A T G G P S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P10979 157 15420 G116 R R D G G Y G G G G G Y G G R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SVM8 158 15684 A117 P A N D R P S A P R A Y G G G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 85 77.1 N.A. 65.1 64.5 N.A. 94.7 84.2 83.7 58.7 N.A. 20.6 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 85 77.6 N.A. 75.5 75 N.A. 96.5 86.8 90.1 66.8 N.A. 29.6 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 13.3 33.3 N.A. 93.3 80 13.3 40 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 20 33.3 N.A. 100 93.3 13.3 53.3 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 44.1 N.A. 22 N.A. N.A.
Protein Similarity: N.A. 56.4 N.A. 30.8 N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. 20 N.A. N.A.
P-Site Similarity: N.A. 20 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 9 0 17 0 9 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 17 17 17 0 9 0 0 9 0 9 0 9 0 % D
% Glu: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 9 0 42 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 67 59 17 17 0 25 17 42 17 59 59 34 59 59 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 17 0 9 0 0 0 0 0 0 0 9 0 % N
% Pro: 9 0 0 0 0 9 0 0 9 0 0 0 0 9 9 % P
% Gln: 0 0 0 9 0 9 9 0 0 0 0 0 0 0 0 % Q
% Arg: 17 9 9 0 67 0 9 0 42 17 9 9 0 9 9 % R
% Ser: 9 9 0 34 0 9 9 59 0 50 0 9 9 9 25 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 42 0 9 0 0 17 9 9 0 0 17 17 59 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _