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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CIRBP All Species: 23.03
Human Site: T43 Identified Species: 46.06
UniProt: Q14011 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14011 NP_001271.1 172 18648 T43 V V V K D R E T Q R S R G F G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094149 200 21970 T43 V V V K D R E T Q R S R G F G
Dog Lupus familis XP_868602 219 23193 T90 V V V K D R E T Q R S R G F G
Cat Felis silvestris
Mouse Mus musculus O89086 153 16586 P31 D H F S S F G P I S E V V V V
Rat Rattus norvegicus Q925G0 155 16836 P31 D H F S S F G P I S E V V V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512332 172 18632 T43 V V V K D R E T Q R S R G F G
Chicken Gallus gallus NP_001026518 190 20955 T43 V V V K D R E T Q R S R G F G
Frog Xenopus laevis Q9DED4 166 17837 R44 V K D R E T K R S R G F G F V
Zebra Danio Brachydanio rerio NP_956311 184 19185 S45 R D R E T D R S R G F G F V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48809 421 44751 S44 V V M K N N E S G R S R G F G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P10979 157 15420 L35 F A S Y G E I L D S K V I T D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SVM8 158 15684 K36 S L R L M S T K L F I G G L S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 85 77.1 N.A. 65.1 64.5 N.A. 94.7 84.2 83.7 58.7 N.A. 20.6 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 85 77.6 N.A. 75.5 75 N.A. 96.5 86.8 90.1 66.8 N.A. 29.6 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 0 0 N.A. 100 100 26.6 0 N.A. 66.6 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 0 0 N.A. 100 100 46.6 20 N.A. 86.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 44.1 N.A. 22 N.A. N.A.
Protein Similarity: N.A. 56.4 N.A. 30.8 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 0 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 9 9 0 42 9 0 0 9 0 0 0 0 0 9 % D
% Glu: 0 0 0 9 9 9 50 0 0 0 17 0 0 0 0 % E
% Phe: 9 0 17 0 0 17 0 0 0 9 9 9 9 59 0 % F
% Gly: 0 0 0 0 9 0 17 0 9 9 9 17 67 0 50 % G
% His: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 17 0 9 0 9 0 0 % I
% Lys: 0 9 0 50 0 0 9 9 0 0 9 0 0 0 0 % K
% Leu: 0 9 0 9 0 0 0 9 9 0 0 0 0 9 0 % L
% Met: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 42 0 0 0 0 0 0 % Q
% Arg: 9 0 17 9 0 42 9 9 9 59 0 50 0 0 0 % R
% Ser: 9 0 9 17 17 9 0 17 9 25 50 0 0 0 9 % S
% Thr: 0 0 0 0 9 9 9 42 0 0 0 0 0 9 9 % T
% Val: 59 50 42 0 0 0 0 0 0 0 0 25 17 25 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _