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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAMK1 All Species: 46.36
Human Site: T181 Identified Species: 78.46
UniProt: Q14012 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14012 NP_003647.1 370 41337 T181 V L S T A C G T P G Y V A P E
Chimpanzee Pan troglodytes XP_516263 370 41302 T181 V L S T A C G T P G Y V A P E
Rhesus Macaque Macaca mulatta XP_001095449 370 41328 T181 V L S T A C G T P G Y V A P E
Dog Lupus familis XP_541780 370 41140 T181 V L S T A C G T P G Y V A P E
Cat Felis silvestris
Mouse Mus musculus Q91YS8 374 41606 T181 V L S T A C G T P G Y V A P E
Rat Rattus norvegicus Q63450 374 41620 T181 V L S T A C G T P G Y V A P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506792 375 41635 T182 V L S T A C G T P G Y V A P E
Chicken Gallus gallus XP_417986 455 50818 T203 I M S T A C G T P G Y V A P E
Frog Xenopus laevis Q6GLS4 377 42906 T184 L I K E P C G T P E Y L A P E
Zebra Danio Brachydanio rerio Q7SY49 436 48676 T183 L I K E P C G T P E Y L A P E
Tiger Blowfish Takifugu rubipres Q9YGM4 421 47309 E183 K D P C G T P E Y L A P E V I
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P49101 513 58063 S229 M Y R D I V G S A Y Y V A P E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42396 490 55361 S186 A F S E L V G S A Y Y V A P E
Baker's Yeast Sacchar. cerevisiae P27466 446 50278 S202 L L Y K P A G S L G Y V A P E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.9 96.4 N.A. 95.9 96.2 N.A. 86.9 54.5 42.1 39.2 38.4 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 99.1 97.3 N.A. 96.7 97 N.A. 89.8 65.4 62.3 58 57.4 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 86.6 53.3 53.3 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 73.3 73.3 0 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 29 N.A. 31.8 32.7 N.A.
Protein Similarity: N.A. 44 N.A. 46.5 49.7 N.A.
P-Site Identity: N.A. 40 N.A. 46.6 53.3 N.A.
P-Site Similarity: N.A. 53.3 N.A. 53.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 58 8 0 0 15 0 8 0 93 0 0 % A
% Cys: 0 0 0 8 0 72 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 22 0 0 0 8 0 15 0 0 8 0 93 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 93 0 0 65 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 15 0 0 8 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 8 0 15 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 22 58 0 0 8 0 0 0 8 8 0 15 0 0 0 % L
% Met: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 22 0 8 0 72 0 0 8 0 93 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 65 0 0 0 0 22 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 58 0 8 0 72 0 0 0 0 0 0 0 % T
% Val: 50 0 0 0 0 15 0 0 0 0 0 79 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 0 0 8 15 93 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _