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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COTL1
All Species:
22.73
Human Site:
T99
Identified Species:
62.5
UniProt:
Q14019
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14019
NP_066972.1
142
15945
T99
A
K
T
G
T
D
K
T
L
V
K
E
V
V
Q
Chimpanzee
Pan troglodytes
XP_001144958
97
10806
V56
T
G
T
D
K
T
L
V
K
E
V
V
Q
N
F
Rhesus Macaque
Macaca mulatta
XP_001112723
142
15953
T99
A
K
T
G
T
D
K
T
L
V
K
E
V
V
Q
Dog
Lupus familis
XP_546800
96
10771
L54
K
T
G
T
D
K
T
L
V
K
E
V
V
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQI6
142
15925
T99
A
K
T
G
T
D
K
T
L
V
K
E
V
V
Q
Rat
Rattus norvegicus
B0BNA5
142
15913
T99
A
K
T
G
T
D
K
T
L
V
K
E
V
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510326
142
15905
T99
A
K
T
G
T
D
K
T
L
V
K
E
V
V
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080794
142
16242
T99
A
K
T
G
T
D
K
T
L
V
K
D
V
V
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573323
163
18541
A118
A
K
M
S
T
D
K
A
L
I
K
D
V
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.6
99.3
63.3
N.A.
95
95
N.A.
90.8
N.A.
75.3
N.A.
N.A.
34.9
N.A.
N.A.
N.A.
Protein Similarity:
100
68.3
100
67.6
N.A.
100
100
N.A.
95
N.A.
86.6
N.A.
N.A.
52.7
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
100
100
N.A.
100
N.A.
93.3
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
20
N.A.
100
100
N.A.
100
N.A.
100
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
78
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
12
78
0
0
0
0
0
23
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
12
12
56
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
12
12
67
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
12
78
0
0
12
12
78
0
12
12
78
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
12
12
78
0
0
0
0
12
0
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
23
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
67
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
12
12
78
12
78
12
12
67
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
12
67
12
23
89
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _