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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYLC2
All Species:
18.79
Human Site:
S174
Identified Species:
82.67
UniProt:
Q14093
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14093
NP_001331.1
348
39079
S174
D
A
E
K
G
K
D
S
A
T
E
S
E
D
E
Chimpanzee
Pan troglodytes
XP_001136500
343
38525
S174
D
A
E
K
G
K
D
S
A
T
E
S
E
D
E
Rhesus Macaque
Macaca mulatta
XP_001110333
371
41411
S174
A
A
E
K
G
K
D
S
A
T
E
S
E
D
E
Dog
Lupus familis
XP_855061
352
39832
S211
D
L
K
K
G
K
E
S
A
T
E
S
E
D
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_001156337
422
46635
S195
N
T
P
K
G
K
D
S
A
S
E
S
E
G
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q32N87
642
72361
S234
E
L
K
K
S
P
S
S
S
S
A
S
S
P
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
73.8
45.1
N.A.
46.4
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.2
80.5
59.9
N.A.
57.8
N.A.
N.A.
N.A.
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
50
0
0
0
0
0
0
84
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
0
67
0
0
0
0
0
0
67
0
% D
% Glu:
17
0
50
0
0
0
17
0
0
0
84
0
84
0
84
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
84
0
0
0
0
0
0
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
34
100
0
84
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
17
0
0
17
0
0
0
0
0
0
0
17
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
17
0
17
100
17
34
0
100
17
0
17
% S
% Thr:
0
17
0
0
0
0
0
0
0
67
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _