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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNI All Species: 14.55
Human Site: S258 Identified Species: 32
UniProt: Q14094 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14094 NP_006826.1 377 42557 S258 Q S S L P L N S V Y V Y R P L
Chimpanzee Pan troglodytes XP_001148321 377 42525 S258 Q S S L P L N S I Y V Y R P L
Rhesus Macaque Macaca mulatta XP_001093947 334 37524 V216 S S L P L N S V Y V Y R P L K
Dog Lupus familis XP_535617 379 42579 S258 Q S S L P L N S V Y V Y R P L
Cat Felis silvestris
Mouse Mus musculus Q9Z2V9 377 42243 S258 Q S A L P L N S V Y V Y R P L
Rat Rattus norvegicus P39950 294 33915 L176 P F E R R N D L N F E R L E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516763 231 25715 L113 Q C M T Y H Q L L Q F K G S M
Chicken Gallus gallus XP_420590 384 42806 P260 Q S S L L P N P V Y V Y S P L
Frog Xenopus laevis NP_001083571 382 42895 A260 Q P P L P P N A V Y V Y S P L
Zebra Danio Brachydanio rerio NP_998386 355 39596 S237 H R L Q I D S S Q L I C C R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794154 365 41226 E246 Q W L I R S R E L I T Y T L F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 87.8 96.5 N.A. 93.9 23.3 N.A. 42.9 79.6 68.3 56.5 N.A. N.A. N.A. N.A. 38.9
Protein Similarity: 100 99.7 88.3 97.8 N.A. 96.8 45 N.A. 50.6 87.2 81.1 71.8 N.A. N.A. N.A. N.A. 55.1
P-Site Identity: 100 93.3 6.6 100 N.A. 93.3 0 N.A. 6.6 73.3 66.6 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 13.3 100 N.A. 100 13.3 N.A. 20 73.3 73.3 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 10 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 10 10 0 0 % C
% Asp: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 10 0 0 10 0 0 10 10 % E
% Phe: 0 10 0 0 0 0 0 0 0 10 10 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % G
% His: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 10 0 0 0 10 10 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % K
% Leu: 0 0 28 55 19 37 0 19 19 10 0 0 10 19 55 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 19 55 0 10 0 0 0 0 0 0 % N
% Pro: 10 10 10 10 46 19 0 10 0 0 0 0 10 55 0 % P
% Gln: 73 0 0 10 0 0 10 0 10 10 0 0 0 0 0 % Q
% Arg: 0 10 0 10 19 0 10 0 0 0 0 19 37 10 0 % R
% Ser: 10 55 37 0 0 10 19 46 0 0 0 0 19 10 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 10 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 10 46 10 55 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 10 55 10 64 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _