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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HNRNPD All Species: 19.7
Human Site: S190 Identified Species: 33.33
UniProt: Q14103 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14103 NP_001003810.1 355 38434 S190 K I F V G G L S P D T P E E K
Chimpanzee Pan troglodytes XP_517193 353 38452 S190 K I F V G G L S P D T P E E K
Rhesus Macaque Macaca mulatta Q28521 320 34202 N157 F V T F D D H N S V D K I V I
Dog Lupus familis XP_857639 355 38370 S190 K I F V G G L S P D T P E E K
Cat Felis silvestris
Mouse Mus musculus Q60668 355 38336 S190 K I F V G G L S P D T P E E K
Rat Rattus norvegicus Q9JJ54 353 38173 S188 K I F V G G L S P D T P E E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505245 302 34393 D139 F V G G L S P D T P E E K I R
Chicken Gallus gallus Q5ZI72 301 33425 F138 I K E Y F G A F G E I E N I E
Frog Xenopus laevis Q7ZX83 293 32595 K128 E T T E E Q I K Q Y F G G F G
Zebra Danio Brachydanio rerio NP_001103930 314 35569 T150 V G G L S P D T P E E K I R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q08473 344 36166 C180 K S Q R K G F C F I T F D S E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22037 346 36325 V179 V L Q K S H M V N G H R C D V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001168848 332 36214 P168 I F V G G L N P E A T E E K I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99383 534 59631 G251 K I F V G G I G P D V R P K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 23.3 99.4 N.A. 97.4 96.6 N.A. 80 59.1 52.9 73.5 N.A. 39.1 N.A. 25 N.A.
Protein Similarity: 100 96 37.4 99.7 N.A. 98.8 98.8 N.A. 81.9 70.1 65 80.5 N.A. 56.6 N.A. 40 N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 0 6.6 0 6.6 N.A. 20 N.A. 0 N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 20 20 13.3 33.3 N.A. 33.3 N.A. 20 N.A.
Percent
Protein Identity: N.A. 61.4 N.A. N.A. 24.7 N.A.
Protein Similarity: N.A. 71.2 N.A. N.A. 38.2 N.A.
P-Site Identity: N.A. 20 N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 8 8 8 8 0 43 8 0 8 8 0 % D
% Glu: 8 0 8 8 8 0 0 0 8 15 15 22 43 36 29 % E
% Phe: 15 8 43 8 8 0 8 8 8 0 8 8 0 8 0 % F
% Gly: 0 8 15 15 50 58 0 8 8 8 0 8 8 0 8 % G
% His: 0 0 0 0 0 8 8 0 0 0 8 0 0 0 0 % H
% Ile: 15 43 0 0 0 0 15 0 0 8 8 0 15 15 15 % I
% Lys: 50 8 0 8 8 0 0 8 0 0 0 15 8 15 36 % K
% Leu: 0 8 0 8 8 8 36 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 8 8 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 8 8 8 50 8 0 36 8 0 0 % P
% Gln: 0 0 15 0 0 8 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 15 0 8 8 % R
% Ser: 0 8 0 0 15 8 0 36 8 0 0 0 0 8 0 % S
% Thr: 0 8 15 0 0 0 0 8 8 0 50 0 0 0 0 % T
% Val: 15 15 8 43 0 0 0 8 0 8 8 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _