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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HNRNPD All Species: 17.88
Human Site: T108 Identified Species: 30.26
UniProt: Q14103 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14103 NP_001003810.1 355 38434 T108 I G G L S W D T T K K D L K D
Chimpanzee Pan troglodytes XP_517193 353 38452 T108 I G G L S W D T T K K D L K D
Rhesus Macaque Macaca mulatta Q28521 320 34202 K87 D G R V V E P K R A V S R E D
Dog Lupus familis XP_857639 355 38370 T108 I G G L S W D T T K K D L K D
Cat Felis silvestris
Mouse Mus musculus Q60668 355 38336 T108 I G G L S W D T T K K D L K D
Rat Rattus norvegicus Q9JJ54 353 38173 K108 G L S W D T T K K D L K D Y F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505245 302 34393 E69 D Y F S K F G E V V D C T L K
Chicken Gallus gallus Q5ZI72 301 33425 G68 I K T D P V T G R S R G F G F
Frog Xenopus laevis Q7ZX83 293 32595 K58 E V L D C T I K T D P V T G R
Zebra Danio Brachydanio rerio NP_001103930 314 35569 V80 Y F T K F G E V V D C T L K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q08473 344 36166 I110 V F T N T E A I D K V S A A D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22037 346 36325 E108 R D D K N R S E S N V S T K R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001168848 332 36214 F98 L K D Y F T K F G E V V D C T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99383 534 59631 T170 I G G L N W D T T E D N L R E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 23.3 99.4 N.A. 97.4 96.6 N.A. 80 59.1 52.9 73.5 N.A. 39.1 N.A. 25 N.A.
Protein Similarity: 100 96 37.4 99.7 N.A. 98.8 98.8 N.A. 81.9 70.1 65 80.5 N.A. 56.6 N.A. 40 N.A.
P-Site Identity: 100 100 13.3 100 N.A. 100 0 N.A. 0 6.6 6.6 13.3 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 0 N.A. 6.6 13.3 6.6 20 N.A. 26.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. 61.4 N.A. N.A. 24.7 N.A.
Protein Similarity: N.A. 71.2 N.A. N.A. 38.2 N.A.
P-Site Identity: N.A. 0 N.A. N.A. 60 N.A.
P-Site Similarity: N.A. 13.3 N.A. N.A. 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 0 8 0 0 8 8 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 8 8 0 8 0 % C
% Asp: 15 8 15 15 8 0 36 0 8 22 15 29 15 0 43 % D
% Glu: 8 0 0 0 0 15 8 15 0 15 0 0 0 8 8 % E
% Phe: 0 15 8 0 15 8 0 8 0 0 0 0 8 0 15 % F
% Gly: 8 43 36 0 0 8 8 8 8 0 0 8 0 15 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 43 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % I
% Lys: 0 15 0 15 8 0 8 22 8 36 29 8 0 43 8 % K
% Leu: 8 8 8 36 0 0 0 0 0 0 8 0 43 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 15 0 0 0 0 8 0 8 0 0 0 % N
% Pro: 0 0 0 0 8 0 8 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 8 0 0 8 0 0 15 0 8 0 8 8 15 % R
% Ser: 0 0 8 8 29 0 8 0 8 8 0 22 0 0 0 % S
% Thr: 0 0 22 0 8 22 15 36 43 0 0 8 22 0 8 % T
% Val: 8 8 0 8 8 8 0 8 15 8 29 15 0 0 0 % V
% Trp: 0 0 0 8 0 36 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 8 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _