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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HNRNPD All Species: 20.91
Human Site: T219 Identified Species: 35.38
UniProt: Q14103 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14103 NP_001003810.1 355 38434 T219 E L P M D N K T N K R R G F C
Chimpanzee Pan troglodytes XP_517193 353 38452 T219 E L P M D N K T N K R R G F C
Rhesus Macaque Macaca mulatta Q28521 320 34202 M186 K A L S K Q E M A S A S S S Q
Dog Lupus familis XP_857639 355 38370 T219 E L P M D N K T N K R R G F C
Cat Felis silvestris
Mouse Mus musculus Q60668 355 38336 T219 E L P M D N K T N K R R G F C
Rat Rattus norvegicus Q9JJ54 353 38173 T217 E L P M D N K T N K R R G F C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505245 302 34393 K168 P M D N K T N K R R G F C F I
Chicken Gallus gallus Q5ZI72 301 33425 E167 F I T Y T D E E P V K K L L E
Frog Xenopus laevis Q7ZX83 293 32595 V157 E R R G F C F V T Y T G E E P
Zebra Danio Brachydanio rerio NP_001103930 314 35569 R179 M E N K T N K R R G F C F I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q08473 344 36166 K209 A G K E V D V K R A T P K P E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22037 346 36325 G208 N R D R E T R G G R S R D G Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001168848 332 36214 N197 L P I D P K L N K R R G F V F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99383 534 59631 T280 Q L M L D K D T G Q S R G F G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 23.3 99.4 N.A. 97.4 96.6 N.A. 80 59.1 52.9 73.5 N.A. 39.1 N.A. 25 N.A.
Protein Similarity: 100 96 37.4 99.7 N.A. 98.8 98.8 N.A. 81.9 70.1 65 80.5 N.A. 56.6 N.A. 40 N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 6.6 0 6.6 13.3 N.A. 0 N.A. 6.6 N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 20 33.3 6.6 13.3 N.A. 6.6 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. 61.4 N.A. N.A. 24.7 N.A.
Protein Similarity: N.A. 71.2 N.A. N.A. 38.2 N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. 40 N.A.
P-Site Similarity: N.A. 13.3 N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 0 8 8 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 8 8 0 36 % C
% Asp: 0 0 15 8 43 15 8 0 0 0 0 0 8 0 0 % D
% Glu: 43 8 0 8 8 0 15 8 0 0 0 0 8 8 15 % E
% Phe: 8 0 0 0 8 0 8 0 0 0 8 8 15 50 8 % F
% Gly: 0 8 0 8 0 0 0 8 15 8 8 15 43 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 0 0 0 0 0 0 8 8 % I
% Lys: 8 0 8 8 15 15 43 15 8 36 8 8 8 0 0 % K
% Leu: 8 43 8 8 0 0 8 0 0 0 0 0 8 8 0 % L
% Met: 8 8 8 36 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 8 0 43 8 8 36 0 0 0 0 0 0 % N
% Pro: 8 8 36 0 8 0 0 0 8 0 0 8 0 8 8 % P
% Gln: 8 0 0 0 0 8 0 0 0 8 0 0 0 0 15 % Q
% Arg: 0 15 8 8 0 0 8 8 22 22 43 50 0 0 0 % R
% Ser: 0 0 0 8 0 0 0 0 0 8 15 8 8 8 0 % S
% Thr: 0 0 8 0 15 15 0 43 8 0 15 0 0 0 8 % T
% Val: 0 0 0 0 8 0 8 8 0 8 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _