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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOB2
All Species:
15.76
Human Site:
S170
Identified Species:
34.67
UniProt:
Q14106
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14106
NP_057356.1
344
36632
S170
S
P
T
F
I
P
R
S
A
Q
P
I
T
F
T
Chimpanzee
Pan troglodytes
XP_001169370
344
36584
S170
S
P
T
F
I
P
R
S
A
Q
P
I
T
F
T
Rhesus Macaque
Macaca mulatta
XP_001104257
335
35811
P162
S
P
S
F
G
Q
S
P
S
P
T
F
I
P
R
Dog
Lupus familis
XP_849289
316
34141
Q146
V
F
V
P
I
G
S
Q
D
S
S
L
S
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM55
345
36780
S170
S
P
T
F
I
P
R
S
A
Q
P
I
T
F
T
Rat
Rattus norvegicus
Q8R5K6
365
40443
R170
V
S
P
T
F
M
P
R
S
T
Q
P
L
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506228
329
34806
P156
S
L
S
N
S
P
S
P
S
F
G
R
S
P
S
Chicken
Gallus gallus
NP_001012552
340
36273
S170
S
P
T
F
I
P
R
S
A
Q
P
I
T
F
T
Frog
Xenopus laevis
P40745
233
26927
N63
A
F
R
C
I
R
I
N
E
C
Q
A
L
D
A
Zebra Danio
Brachydanio rerio
NP_998139
322
35292
S150
S
E
P
V
G
V
S
S
E
S
S
S
P
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573104
564
59093
S170
Q
S
G
S
S
P
H
S
A
A
S
S
S
P
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96.8
87.5
N.A.
89.5
50.6
N.A.
84.3
82.8
21.7
61
N.A.
29.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
96.8
90.1
N.A.
92.7
64.1
N.A.
87.2
86.9
37.2
72.9
N.A.
43.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
6.6
N.A.
100
0
N.A.
13.3
100
6.6
13.3
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
26.6
N.A.
100
6.6
N.A.
40
100
20
13.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
46
10
0
10
0
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% D
% Glu:
0
10
0
0
0
0
0
0
19
0
0
0
0
0
0
% E
% Phe:
0
19
0
46
10
0
0
0
0
10
0
10
0
37
10
% F
% Gly:
0
0
10
0
19
10
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
55
0
10
0
0
0
0
37
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
10
19
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
46
19
10
0
55
10
19
0
10
37
10
10
28
10
% P
% Gln:
10
0
0
0
0
10
0
10
0
37
19
0
0
0
0
% Q
% Arg:
0
0
10
0
0
10
37
10
0
0
0
10
0
0
10
% R
% Ser:
64
19
19
10
19
0
37
55
28
19
28
19
28
10
19
% S
% Thr:
0
0
37
10
0
0
0
0
0
10
10
0
37
10
46
% T
% Val:
19
0
10
10
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _