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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCARB2
All Species:
24.24
Human Site:
S282
Identified Species:
44.44
UniProt:
Q14108
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14108
NP_005497.1
478
54290
S282
R
S
V
Y
I
T
F
S
D
Y
E
S
V
Q
G
Chimpanzee
Pan troglodytes
XP_517214
478
54291
S282
R
S
V
Y
I
T
F
S
D
Y
E
S
V
Q
G
Rhesus Macaque
Macaca mulatta
XP_001096458
478
54263
S282
R
S
V
Y
I
T
F
S
D
Y
E
S
V
Q
G
Dog
Lupus familis
XP_535612
447
50655
D252
S
V
Y
I
T
F
S
D
F
K
S
V
Q
G
L
Cat
Felis silvestris
Mouse
Mus musculus
O35114
478
54026
S282
R
S
V
H
I
T
F
S
S
F
E
N
V
E
G
Rat
Rattus norvegicus
P27615
478
54072
S282
R
S
V
Y
I
T
F
S
S
F
E
N
V
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518101
480
53897
T283
R
S
V
Y
V
G
F
T
D
S
V
D
V
R
G
Chicken
Gallus gallus
XP_420593
481
53889
G285
Y
L
V
Y
D
S
S
G
S
V
A
G
V
P
T
Frog
Xenopus laevis
NP_001088246
483
54672
E286
Y
A
V
Y
E
S
S
E
N
I
K
D
I
S
V
Zebra Danio
Brachydanio rerio
NP_775366
531
60216
M290
H
L
G
Y
V
R
D
M
E
V
K
G
I
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27367
457
52316
T262
P
C
G
I
V
N
G
T
T
G
D
M
F
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11124
563
62684
D362
R
T
I
H
F
V
F
D
R
E
V
T
V
K
G
Sea Urchin
Strong. purpuratus
XP_785055
366
41141
T171
H
K
V
C
V
T
H
T
V
H
E
Y
I
W
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.7
79.9
N.A.
85.7
85.9
N.A.
65.2
59.2
51.9
41.6
N.A.
30.9
N.A.
28.6
31.5
Protein Similarity:
100
99.7
99.5
89.5
N.A.
95.8
95.1
N.A.
81
77.5
71.6
63.4
N.A.
49.1
N.A.
46.1
46.4
P-Site Identity:
100
100
100
0
N.A.
66.6
73.3
N.A.
53.3
20
13.3
6.6
N.A.
0
N.A.
26.6
26.6
P-Site Similarity:
100
100
100
0
N.A.
93.3
93.3
N.A.
73.3
26.6
46.6
33.3
N.A.
20
N.A.
60
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
16
31
0
8
16
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
8
8
8
47
0
0
16
0
% E
% Phe:
0
0
0
0
8
8
54
0
8
16
0
0
8
0
0
% F
% Gly:
0
0
16
0
0
8
8
8
0
8
0
16
0
8
62
% G
% His:
16
0
0
16
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
16
39
0
0
0
0
8
0
0
24
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
8
16
0
0
8
0
% K
% Leu:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
0
16
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
24
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
24
0
% Q
% Arg:
54
0
0
0
0
8
0
0
8
0
0
0
0
8
0
% R
% Ser:
8
47
0
0
0
16
24
39
24
8
8
24
0
8
0
% S
% Thr:
0
8
0
0
8
47
0
24
8
0
0
8
0
0
8
% T
% Val:
0
8
70
0
31
8
0
0
8
16
16
8
62
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
16
0
8
62
0
0
0
0
0
24
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _