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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCARB2
All Species:
33.03
Human Site:
S414
Identified Species:
60.56
UniProt:
Q14108
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14108
NP_005497.1
478
54290
S414
P
V
M
Y
L
N
E
S
V
H
I
D
K
E
T
Chimpanzee
Pan troglodytes
XP_517214
478
54291
S414
P
V
M
Y
L
N
E
S
V
H
I
D
K
E
T
Rhesus Macaque
Macaca mulatta
XP_001096458
478
54263
S414
P
V
M
Y
L
N
E
S
V
L
I
D
K
E
T
Dog
Lupus familis
XP_535612
447
50655
V384
V
M
Y
I
N
E
S
V
L
I
D
K
D
T
A
Cat
Felis silvestris
Mouse
Mus musculus
O35114
478
54026
S414
P
V
M
Y
L
N
E
S
V
L
I
D
K
E
T
Rat
Rattus norvegicus
P27615
478
54072
S414
P
V
M
Y
L
N
E
S
V
L
I
D
K
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518101
480
53897
S415
P
V
M
Y
L
N
E
S
V
L
I
D
E
D
S
Chicken
Gallus gallus
XP_420593
481
53889
S417
P
V
M
Y
I
N
E
S
V
L
I
D
E
A
S
Frog
Xenopus laevis
NP_001088246
483
54672
S418
P
V
M
H
L
N
E
S
V
L
I
D
D
K
S
Zebra Danio
Brachydanio rerio
NP_775366
531
60216
T422
P
I
M
Y
V
N
E
T
A
T
I
D
D
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27367
457
52316
Q394
P
I
T
G
V
P
V
Q
V
H
G
R
I
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11124
563
62684
G494
S
Y
S
V
M
R
P
G
A
Y
P
L
A
W
V
Sea Urchin
Strong. purpuratus
XP_785055
366
41141
F303
F
S
P
P
S
Y
L
F
A
N
Y
T
I
Y
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.7
79.9
N.A.
85.7
85.9
N.A.
65.2
59.2
51.9
41.6
N.A.
30.9
N.A.
28.6
31.5
Protein Similarity:
100
99.7
99.5
89.5
N.A.
95.8
95.1
N.A.
81
77.5
71.6
63.4
N.A.
49.1
N.A.
46.1
46.4
P-Site Identity:
100
100
93.3
0
N.A.
93.3
93.3
N.A.
73.3
66.6
66.6
53.3
N.A.
20
N.A.
0
0
P-Site Similarity:
100
100
93.3
13.3
N.A.
93.3
93.3
N.A.
93.3
86.6
86.6
80
N.A.
40
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
24
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
70
24
8
0
% D
% Glu:
0
0
0
0
0
8
70
0
0
0
0
0
16
47
0
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
0
0
8
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
24
0
0
0
0
0
% H
% Ile:
0
16
0
8
8
0
0
0
0
8
70
0
16
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
39
8
0
% K
% Leu:
0
0
0
0
54
0
8
0
8
47
0
8
0
0
0
% L
% Met:
0
8
70
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
70
0
0
0
8
0
0
0
0
0
% N
% Pro:
77
0
8
8
0
8
8
0
0
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
8
8
0
8
0
8
62
0
0
0
0
0
0
31
% S
% Thr:
0
0
8
0
0
0
0
8
0
8
0
8
0
8
39
% T
% Val:
8
62
0
8
16
0
8
8
70
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
8
62
0
8
0
0
0
8
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _