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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCARB2
All Species:
24.85
Human Site:
S427
Identified Species:
45.56
UniProt:
Q14108
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14108
NP_005497.1
478
54290
S427
E
T
A
S
R
L
K
S
M
I
N
T
T
L
I
Chimpanzee
Pan troglodytes
XP_517214
478
54291
S427
E
T
A
S
R
L
K
S
M
I
N
T
T
L
I
Rhesus Macaque
Macaca mulatta
XP_001096458
478
54263
S427
E
T
A
S
R
L
K
S
V
I
N
T
T
L
I
Dog
Lupus familis
XP_535612
447
50655
V397
T
A
S
R
L
K
S
V
I
N
T
T
L
I
I
Cat
Felis silvestris
Mouse
Mus musculus
O35114
478
54026
S427
E
T
A
N
Q
L
K
S
V
I
N
T
T
L
V
Rat
Rattus norvegicus
P27615
478
54072
S427
E
T
A
S
Q
L
K
S
V
I
N
T
T
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518101
480
53897
S428
D
S
V
K
K
L
R
S
V
L
N
T
M
M
V
Chicken
Gallus gallus
XP_420593
481
53889
H430
A
S
A
N
K
L
K
H
V
L
L
E
A
S
V
Frog
Xenopus laevis
NP_001088246
483
54672
S431
K
S
A
E
K
L
R
S
I
I
L
Q
G
R
M
Zebra Danio
Brachydanio rerio
NP_775366
531
60216
M435
E
S
A
A
Q
M
R
M
L
L
L
I
V
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27367
457
52316
P407
Q
I
N
M
M
I
E
P
D
D
D
F
D
I
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11124
563
62684
M507
W
V
N
E
S
F
Y
M
D
Q
N
T
I
D
Q
Sea Urchin
Strong. purpuratus
XP_785055
366
41141
C316
Y
P
P
N
I
G
F
C
T
P
D
K
A
H
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.7
79.9
N.A.
85.7
85.9
N.A.
65.2
59.2
51.9
41.6
N.A.
30.9
N.A.
28.6
31.5
Protein Similarity:
100
99.7
99.5
89.5
N.A.
95.8
95.1
N.A.
81
77.5
71.6
63.4
N.A.
49.1
N.A.
46.1
46.4
P-Site Identity:
100
100
93.3
13.3
N.A.
73.3
86.6
N.A.
26.6
20
26.6
13.3
N.A.
0
N.A.
13.3
0
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
80
60
66.6
66.6
N.A.
33.3
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
62
8
0
0
0
0
0
0
0
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
0
0
0
0
16
8
16
0
8
8
0
% D
% Glu:
47
0
0
16
0
0
8
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
8
8
0
0
16
47
0
8
8
16
39
% I
% Lys:
8
0
0
8
24
8
47
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
0
0
8
62
0
0
8
24
24
0
8
39
0
% L
% Met:
0
0
0
8
8
8
0
16
16
0
0
0
8
8
8
% M
% Asn:
0
0
16
24
0
0
0
0
0
8
54
0
0
0
0
% N
% Pro:
0
8
8
0
0
0
0
8
0
8
0
0
0
0
0
% P
% Gln:
8
0
0
0
24
0
0
0
0
8
0
8
0
0
8
% Q
% Arg:
0
0
0
8
24
0
24
0
0
0
0
0
0
8
0
% R
% Ser:
0
31
8
31
8
0
8
54
0
0
0
0
0
8
0
% S
% Thr:
8
39
0
0
0
0
0
0
8
0
8
62
39
8
0
% T
% Val:
0
8
8
0
0
0
0
8
39
0
0
0
8
0
31
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _