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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCARB2
All Species:
22.42
Human Site:
T208
Identified Species:
41.11
UniProt:
Q14108
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14108
NP_005497.1
478
54290
T208
L
F
Y
E
K
N
G
T
N
D
G
D
Y
V
F
Chimpanzee
Pan troglodytes
XP_517214
478
54291
T208
L
F
Y
E
K
N
G
T
N
D
G
D
Y
V
F
Rhesus Macaque
Macaca mulatta
XP_001096458
478
54263
T208
L
F
Y
E
K
N
G
T
N
D
G
D
Y
V
F
Dog
Lupus familis
XP_535612
447
50655
N178
Y
Y
G
K
N
G
T
N
D
G
D
Y
V
F
L
Cat
Felis silvestris
Mouse
Mus musculus
O35114
478
54026
T208
L
F
Y
E
R
N
G
T
N
D
G
E
Y
V
F
Rat
Rattus norvegicus
P27615
478
54072
T208
L
F
Y
E
R
N
G
T
N
D
G
E
Y
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518101
480
53897
T209
L
F
Y
G
K
N
A
T
D
D
G
E
Y
V
F
Chicken
Gallus gallus
XP_420593
481
53889
G211
K
M
N
G
T
D
D
G
E
Y
V
F
L
S
G
Frog
Xenopus laevis
NP_001088246
483
54672
G212
K
M
N
T
T
D
D
G
E
Y
V
F
L
S
G
Zebra Danio
Brachydanio rerio
NP_775366
531
60216
G216
N
K
N
G
T
H
E
G
E
F
V
F
H
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27367
457
52316
D188
W
I
F
E
G
Y
Q
D
N
I
T
D
F
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11124
563
62684
T288
P
L
K
A
G
Y
M
T
E
F
R
S
I
S
N
Sea Urchin
Strong. purpuratus
XP_785055
366
41141
V97
Y
R
E
E
R
P
K
V
N
V
T
E
H
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.7
79.9
N.A.
85.7
85.9
N.A.
65.2
59.2
51.9
41.6
N.A.
30.9
N.A.
28.6
31.5
Protein Similarity:
100
99.7
99.5
89.5
N.A.
95.8
95.1
N.A.
81
77.5
71.6
63.4
N.A.
49.1
N.A.
46.1
46.4
P-Site Identity:
100
100
100
0
N.A.
86.6
86.6
N.A.
73.3
0
0
0
N.A.
20
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
86.6
6.6
6.6
13.3
N.A.
40
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
16
16
8
16
47
8
31
0
0
0
% D
% Glu:
0
0
8
54
0
0
8
0
31
0
0
31
0
8
0
% E
% Phe:
0
47
8
0
0
0
0
0
0
16
0
24
8
8
47
% F
% Gly:
0
0
8
24
16
8
39
24
0
8
47
0
0
0
24
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
16
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
16
8
8
8
31
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
47
8
0
0
0
0
0
0
0
0
0
0
16
8
8
% L
% Met:
0
16
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
24
0
8
47
0
8
54
0
0
0
0
0
24
% N
% Pro:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
24
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
8
0
24
0
% S
% Thr:
0
0
0
8
24
0
8
54
0
0
16
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
8
0
8
24
0
8
47
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
8
47
0
0
16
0
0
0
16
0
8
47
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _