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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCARB2 All Species: 29.39
Human Site: T47 Identified Species: 53.89
UniProt: Q14108 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14108 NP_005497.1 478 54290 T47 K I V L R N G T E A F D S W E
Chimpanzee Pan troglodytes XP_517214 478 54291 T47 K I V L R N G T E A F D S W E
Rhesus Macaque Macaca mulatta XP_001096458 478 54263 T47 K I V L R N G T E A F D S W E
Dog Lupus familis XP_535612 447 50655 F19 L R N G S E T F D S W K K P P
Cat Felis silvestris
Mouse Mus musculus O35114 478 54026 T47 N M V L Q N G T K V F N S W E
Rat Rattus norvegicus P27615 478 54072 T47 N M V L Q N G T K V F D S W E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518101 480 53897 T48 N V V L K N G T D A F E S W E
Chicken Gallus gallus XP_420593 481 53889 T47 G T V L K N G T E T F E A W E
Frog Xenopus laevis NP_001088246 483 54672 S47 A T V L K N E S E V F E D W A
Zebra Danio Brachydanio rerio NP_775366 531 60216 S49 E I T L A E N S R V L D G W I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27367 457 52316 I29 F L L L G I L I V V F W P G I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q11124 563 62684 V47 N Q I N D S K V L G L N A D G
Sea Urchin Strong. purpuratus XP_785055 366 41141
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.7 79.9 N.A. 85.7 85.9 N.A. 65.2 59.2 51.9 41.6 N.A. 30.9 N.A. 28.6 31.5
Protein Similarity: 100 99.7 99.5 89.5 N.A. 95.8 95.1 N.A. 81 77.5 71.6 63.4 N.A. 49.1 N.A. 46.1 46.4
P-Site Identity: 100 100 100 0 N.A. 60 66.6 N.A. 66.6 60 40 26.6 N.A. 13.3 N.A. 0 0
P-Site Similarity: 100 100 100 20 N.A. 86.6 86.6 N.A. 93.3 80 60 40 N.A. 26.6 N.A. 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 0 0 0 31 0 0 16 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 16 0 0 39 8 8 0 % D
% Glu: 8 0 0 0 0 16 8 0 39 0 0 24 0 0 54 % E
% Phe: 8 0 0 0 0 0 0 8 0 0 70 0 0 0 0 % F
% Gly: 8 0 0 8 8 0 54 0 0 8 0 0 8 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 31 8 0 0 8 0 8 0 0 0 0 0 0 16 % I
% Lys: 24 0 0 0 24 0 8 0 16 0 0 8 8 0 0 % K
% Leu: 8 8 8 77 0 0 8 0 8 0 16 0 0 0 0 % L
% Met: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 31 0 8 8 0 62 8 0 0 0 0 16 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 8 % P
% Gln: 0 8 0 0 16 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 24 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 8 8 0 16 0 8 0 0 47 0 0 % S
% Thr: 0 16 8 0 0 0 8 54 0 8 0 0 0 0 0 % T
% Val: 0 8 62 0 0 0 0 8 8 39 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 8 0 70 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _