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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP8
All Species:
19.39
Human Site:
S943
Identified Species:
47.41
UniProt:
Q14114
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14114
NP_001018064.1
963
105634
S943
Q
L
P
K
N
P
L
S
E
L
P
V
V
K
S
Chimpanzee
Pan troglodytes
XP_513416
955
105121
S935
Q
L
P
K
N
P
L
S
E
L
P
V
V
K
S
Rhesus Macaque
Macaca mulatta
XP_001112940
959
105115
S939
Q
L
P
R
N
P
L
S
E
L
P
V
V
K
S
Dog
Lupus familis
XP_546704
1149
124413
S1129
Q
L
P
K
N
P
L
S
E
L
P
V
V
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q924X6
996
109799
S976
Q
L
P
K
N
P
L
S
E
L
P
V
V
K
C
Rat
Rattus norvegicus
P98166
873
96523
S853
S
I
D
I
G
R
H
S
A
S
V
G
H
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510419
931
103761
S912
D
E
I
H
I
C
K
S
Q
D
G
Y
T
Y
P
Chicken
Gallus gallus
Q98931
917
101361
A897
E
I
H
I
G
R
T
A
Q
I
G
H
V
Y
P
Frog
Xenopus laevis
Q99087
909
101277
S890
D
Q
V
H
I
C
R
S
Q
D
G
Y
T
Y
P
Zebra Danio
Brachydanio rerio
XP_001920116
1054
116614
P1001
S
I
P
E
S
M
R
P
L
V
L
H
L
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
96.5
77.2
N.A.
86.8
45.6
N.A.
44.9
66.2
43.2
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.7
97.5
79.1
N.A.
90.3
60.6
N.A.
59
75.6
58.6
67.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
6.6
N.A.
6.6
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
13.3
40
13.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
20
% C
% Asp:
20
0
10
0
0
0
0
0
0
20
0
0
0
0
0
% D
% Glu:
10
10
0
10
0
0
0
0
50
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
20
0
0
0
0
0
30
10
0
0
0
% G
% His:
0
0
10
20
0
0
10
0
0
0
0
20
10
0
0
% H
% Ile:
0
30
10
20
20
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
40
0
0
10
0
0
0
0
0
0
50
0
% K
% Leu:
0
50
0
0
0
0
50
0
10
50
10
0
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
60
0
0
50
0
10
0
0
50
0
0
0
30
% P
% Gln:
50
10
0
0
0
0
0
0
30
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
20
20
0
0
0
0
0
0
0
0
% R
% Ser:
20
0
0
0
10
0
0
80
0
10
0
0
0
10
30
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
20
10
0
% T
% Val:
0
0
10
0
0
0
0
0
0
10
10
50
60
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
20
0
30
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _