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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL18
All Species:
20.91
Human Site:
S184
Identified Species:
76.67
UniProt:
Q14116
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14116
NP_001553.1
193
22326
S184
E
D
E
L
G
D
R
S
I
M
F
T
V
Q
N
Chimpanzee
Pan troglodytes
XP_001146653
189
21877
S180
E
D
E
L
G
D
R
S
I
M
F
T
V
Q
N
Rhesus Macaque
Macaca mulatta
NP_001028006
193
22307
S184
K
D
E
L
G
D
R
S
I
M
F
T
V
Q
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70380
192
22117
S181
K
D
E
N
G
D
K
S
V
M
F
T
L
T
N
Rat
Rattus norvegicus
P97636
194
22285
S183
K
D
E
N
G
D
K
S
V
M
F
T
L
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514335
150
17201
S142
C
E
K
K
Q
N
D
S
Y
F
T
M
I
L
K
Chicken
Gallus gallus
Q8QFQ8
196
22769
T184
E
D
E
V
D
E
T
T
K
F
V
T
S
H
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
95.8
N.A.
N.A.
63.7
61.8
N.A.
32.1
36.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.9
98.9
N.A.
N.A.
81.3
79.3
N.A.
49.2
54
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
60
60
N.A.
6.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
33.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
86
0
0
15
72
15
0
0
0
0
0
0
0
0
% D
% Glu:
43
15
86
0
0
15
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
29
72
0
0
0
0
% F
% Gly:
0
0
0
0
72
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% H
% Ile:
0
0
0
0
0
0
0
0
43
0
0
0
15
0
0
% I
% Lys:
43
0
15
15
0
0
29
0
15
0
0
0
0
0
15
% K
% Leu:
0
0
0
43
0
0
0
0
0
0
0
0
29
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
72
0
15
0
0
0
% M
% Asn:
0
0
0
29
0
15
0
0
0
0
0
0
0
0
86
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
15
0
0
0
0
0
0
0
0
43
0
% Q
% Arg:
0
0
0
0
0
0
43
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
86
0
0
0
0
15
0
0
% S
% Thr:
0
0
0
0
0
0
15
15
0
0
15
86
0
29
0
% T
% Val:
0
0
0
15
0
0
0
0
29
0
15
0
43
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _