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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPYS
All Species:
18.18
Human Site:
T116
Identified Species:
40
UniProt:
Q14117
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14117
NP_001376.1
519
56630
T116
S
L
I
E
A
F
E
T
W
R
S
W
A
D
P
Chimpanzee
Pan troglodytes
XP_001161598
677
73426
Q227
S
L
L
A
A
F
D
Q
W
R
E
W
A
D
S
Rhesus Macaque
Macaca mulatta
XP_001086073
519
56693
T116
S
L
I
E
A
F
E
T
W
R
S
W
A
D
P
Dog
Lupus familis
XP_532301
518
56420
T115
S
L
I
Q
A
F
E
T
W
R
S
W
A
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQF5
519
56706
T116
S
L
I
E
A
F
E
T
W
R
N
W
A
D
P
Rat
Rattus norvegicus
Q63150
519
56796
T116
S
L
I
E
A
F
E
T
W
R
N
W
A
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512357
612
66452
K164
S
L
A
E
A
Y
E
K
W
R
E
W
A
D
G
Chicken
Gallus gallus
Q90635
572
62312
Q122
S
L
L
T
A
F
D
Q
W
R
E
W
A
D
S
Frog
Xenopus laevis
O13022
571
62110
K122
S
L
T
E
A
F
E
K
W
R
E
W
A
D
G
Zebra Danio
Brachydanio rerio
Q52PJ5
567
61525
R122
S
L
L
E
A
F
D
R
W
S
K
W
A
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18677
520
56275
R108
S
L
L
V
A
Y
D
R
W
R
G
W
A
D
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.5
97.8
92.2
N.A.
88.4
90.1
N.A.
50.1
55.4
54.4
53.9
N.A.
N.A.
N.A.
56.3
N.A.
Protein Similarity:
100
58.6
98.8
95.7
N.A.
93.4
94.2
N.A.
65.3
69.5
69.1
69.6
N.A.
N.A.
N.A.
70.7
N.A.
P-Site Identity:
100
60
100
93.3
N.A.
93.3
93.3
N.A.
66.6
60
73.3
60
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
100
100
N.A.
73.3
73.3
73.3
73.3
N.A.
N.A.
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
100
0
0
0
0
0
0
0
100
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
37
0
0
0
0
0
0
100
0
% D
% Glu:
0
0
0
64
0
0
64
0
0
0
37
0
0
0
10
% E
% Phe:
0
0
0
0
0
82
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
46
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
19
0
0
10
0
0
0
0
% K
% Leu:
0
100
37
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
55
% P
% Gln:
0
0
0
10
0
0
0
19
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
19
0
91
0
0
0
0
0
% R
% Ser:
100
0
0
0
0
0
0
0
0
10
28
0
0
0
19
% S
% Thr:
0
0
10
10
0
0
0
46
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
100
0
0
100
0
0
0
% W
% Tyr:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _