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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPYS All Species: 39.7
Human Site: T307 Identified Species: 87.33
UniProt: Q14117 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14117 NP_001376.1 519 56630 T307 P L R P D P S T P D F L M N L
Chimpanzee Pan troglodytes XP_001161598 677 73426 T418 P L S P D P T T P D F L N S L
Rhesus Macaque Macaca mulatta XP_001086073 519 56693 T307 P L R P D P S T P D F L M N L
Dog Lupus familis XP_532301 518 56420 T306 P L R P D P S T P D F L M N L
Cat Felis silvestris
Mouse Mus musculus Q9EQF5 519 56706 T307 P L R P D P L T P G F L M D L
Rat Rattus norvegicus Q63150 519 56796 T307 P L R P D P S T P G F L M N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512357 612 66452 T355 P L S P D P T T P D Y I S S L
Chicken Gallus gallus Q90635 572 62312 T313 P L S P D P T T P D F L N S L
Frog Xenopus laevis O13022 571 62110 T313 P L S P D P T T P D Y I N S L
Zebra Danio Brachydanio rerio Q52PJ5 567 61525 T313 P L S P D P T T P D Y L N T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18677 520 56275 T300 P L S R D P S T P S A L M K L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.5 97.8 92.2 N.A. 88.4 90.1 N.A. 50.1 55.4 54.4 53.9 N.A. N.A. N.A. 56.3 N.A.
Protein Similarity: 100 58.6 98.8 95.7 N.A. 93.4 94.2 N.A. 65.3 69.5 69.1 69.6 N.A. N.A. N.A. 70.7 N.A.
P-Site Identity: 100 73.3 100 100 N.A. 80 93.3 N.A. 60 73.3 60 66.6 N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 86.6 93.3 N.A. 86.6 86.6 86.6 80 N.A. N.A. N.A. 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 100 0 0 0 0 73 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 64 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 100 0 0 0 0 10 0 0 0 0 82 0 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 55 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 37 37 0 % N
% Pro: 100 0 0 91 0 100 0 0 100 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 46 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 55 0 0 0 46 0 0 10 0 0 10 37 0 % S
% Thr: 0 0 0 0 0 0 46 100 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _