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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAG1 All Species: 6.06
Human Site: S166 Identified Species: 13.33
UniProt: Q14118 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14118 NP_004384.2 895 97441 S166 E D H S E L Q S V R T A S P D
Chimpanzee Pan troglodytes XP_001164638 895 97501 S166 E D H S E L Q S V R T A S P D
Rhesus Macaque Macaca mulatta XP_001108323 894 97378 T168 S E L Q S V R T A F P D P G E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q62165 893 96886 A167 N E P Q S V R A A S S D P G E
Rat Rattus norvegicus XP_343484 893 96688 A167 S E P Q S V R A A S S D P G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509725 896 98376 V168 N E P Q S V R V A S Q D L N E
Chicken Gallus gallus NP_001091009 896 97593 A168 S E P Q S L R A A A Q E A G D
Frog Xenopus laevis NP_001082480 886 97556 G167 P Q S V R V A G Q E T A E A I
Zebra Danio Brachydanio rerio NP_775381 866 94555 A178 E T D P F Q L A I Q Q S A S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392358 704 79379 A66 T N T T T T M A P T T A S T T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786589 869 94279 V172 C P P E K P A V R A T I I L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.4 N.A. N.A. 93.1 92.6 N.A. 85.4 77.7 68.9 60.8 N.A. N.A. 20.6 N.A. 30
Protein Similarity: 100 99.4 98 N.A. N.A. 95.8 95.3 N.A. 91.8 87.3 81 73.5 N.A. N.A. 38.3 N.A. 48.7
P-Site Identity: 100 100 0 N.A. N.A. 0 0 N.A. 0 13.3 13.3 6.6 N.A. N.A. 20 N.A. 13.3
P-Site Similarity: 100 100 33.3 N.A. N.A. 40 40 N.A. 26.6 40 20 46.6 N.A. N.A. 40 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 19 46 46 19 0 37 19 10 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 10 0 0 0 0 0 0 0 0 37 0 0 37 % D
% Glu: 28 46 0 10 19 0 0 0 0 10 0 10 10 0 37 % E
% Phe: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 0 0 37 0 % G
% His: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 10 10 0 10 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 28 10 0 0 0 0 0 10 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 19 10 0 0 0 0 0 0 0 0 0 0 0 10 10 % N
% Pro: 10 10 46 10 0 10 0 0 10 0 10 0 28 19 0 % P
% Gln: 0 10 0 46 0 10 19 0 10 10 28 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 46 0 10 19 0 0 0 0 0 % R
% Ser: 28 0 10 19 46 0 0 19 0 28 19 10 28 10 0 % S
% Thr: 10 10 10 10 10 10 0 10 0 10 46 0 0 10 10 % T
% Val: 0 0 0 10 0 46 0 19 19 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _