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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DAG1
All Species:
26.36
Human Site:
S550
Identified Species:
58
UniProt:
Q14118
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14118
NP_004384.2
895
97441
S550
Q
Q
L
V
G
E
K
S
W
V
Q
F
N
S
N
Chimpanzee
Pan troglodytes
XP_001164638
895
97501
S550
Q
Q
L
V
G
E
K
S
W
V
Q
F
N
S
N
Rhesus Macaque
Macaca mulatta
XP_001108323
894
97378
S549
Q
Q
L
V
G
E
K
S
W
V
Q
F
N
S
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62165
893
96886
S548
Q
Q
L
V
G
E
K
S
W
V
Q
F
N
S
N
Rat
Rattus norvegicus
XP_343484
893
96688
S548
Q
Q
L
V
G
E
K
S
W
V
Q
F
N
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509725
896
98376
S551
Q
Q
M
V
G
E
K
S
W
V
Q
F
N
S
N
Chicken
Gallus gallus
NP_001091009
896
97593
S551
Q
Q
M
I
E
E
N
S
W
V
Q
F
N
S
T
Frog
Xenopus laevis
NP_001082480
886
97556
M539
K
A
S
A
G
E
K
M
W
V
M
L
N
S
T
Zebra Danio
Brachydanio rerio
NP_775381
866
94555
A553
K
H
E
Y
F
M
Q
A
T
D
K
G
G
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392358
704
79379
P415
N
Q
E
F
Y
G
V
P
M
R
S
D
V
G
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786589
869
94279
F527
G
T
L
L
S
S
D
F
W
L
K
F
D
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
N.A.
N.A.
93.1
92.6
N.A.
85.4
77.7
68.9
60.8
N.A.
N.A.
20.6
N.A.
30
Protein Similarity:
100
99.4
98
N.A.
N.A.
95.8
95.3
N.A.
91.8
87.3
81
73.5
N.A.
N.A.
38.3
N.A.
48.7
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
93.3
66.6
46.6
0
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
80
53.3
26.6
N.A.
N.A.
6.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
10
0
10
10
0
0
% D
% Glu:
0
0
19
0
10
73
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
10
0
0
10
0
0
0
73
0
0
0
% F
% Gly:
10
0
0
0
64
10
0
0
0
0
0
10
10
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
0
0
0
0
0
64
0
0
0
19
0
0
10
0
% K
% Leu:
0
0
55
10
0
0
0
0
0
10
0
10
0
10
0
% L
% Met:
0
0
19
0
0
10
0
10
10
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
10
0
0
0
0
0
73
0
55
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
64
73
0
0
0
0
10
0
0
0
64
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% R
% Ser:
0
0
10
0
10
10
0
64
0
0
10
0
0
73
0
% S
% Thr:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
19
% T
% Val:
0
0
0
55
0
0
10
0
0
73
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _