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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAG1 All Species: 28.18
Human Site: T442 Identified Species: 62
UniProt: Q14118 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14118 NP_004384.2 895 97441 T442 A T P S T D S T T T T T R R P
Chimpanzee Pan troglodytes XP_001164638 895 97501 T442 A T P S T D S T T T T T R R P
Rhesus Macaque Macaca mulatta XP_001108323 894 97378 S441 A T P S T D S S T T T T R R P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q62165 893 96886 S440 A T P S T D S S T T T T R R P
Rat Rattus norvegicus XP_343484 893 96688 S440 A T P S T D S S T T T T R R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509725 896 98376 S441 A T P S T T D S S T T T T T R
Chicken Gallus gallus NP_001091009 896 97593 S441 A T P S T T D S S T A T T R R
Frog Xenopus laevis NP_001082480 886 97556 T438 P P T T D S S T T T T K K P T
Zebra Danio Brachydanio rerio NP_775381 866 94555 T451 P I P R E P K T T T T K P P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392358 704 79379 Y319 I R V K R V V Y Q G I G Q C E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786589 869 94279 P431 S T P V A S I P V D T M A P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.4 N.A. N.A. 93.1 92.6 N.A. 85.4 77.7 68.9 60.8 N.A. N.A. 20.6 N.A. 30
Protein Similarity: 100 99.4 98 N.A. N.A. 95.8 95.3 N.A. 91.8 87.3 81 73.5 N.A. N.A. 38.3 N.A. 48.7
P-Site Identity: 100 100 93.3 N.A. N.A. 93.3 93.3 N.A. 53.3 53.3 33.3 33.3 N.A. N.A. 0 N.A. 20
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 66.6 66.6 46.6 33.3 N.A. N.A. 6.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 64 0 0 0 10 0 0 0 0 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 10 46 19 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 10 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 10 0 0 0 0 19 10 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 19 10 82 0 0 10 0 10 0 0 0 0 10 28 46 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % Q
% Arg: 0 10 0 10 10 0 0 0 0 0 0 0 46 55 28 % R
% Ser: 10 0 0 64 0 19 55 46 19 0 0 0 0 0 0 % S
% Thr: 0 73 10 10 64 19 0 37 64 82 82 64 19 10 19 % T
% Val: 0 0 10 10 0 10 10 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _