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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DAG1
All Species:
18.79
Human Site:
T450
Identified Species:
41.33
UniProt:
Q14118
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14118
NP_004384.2
895
97441
T450
T
T
T
T
R
R
P
T
K
K
P
R
T
P
R
Chimpanzee
Pan troglodytes
XP_001164638
895
97501
T450
T
T
T
T
R
R
P
T
K
K
P
R
T
P
R
Rhesus Macaque
Macaca mulatta
XP_001108323
894
97378
T449
T
T
T
T
R
R
P
T
K
K
P
R
T
P
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62165
893
96886
T448
T
T
T
T
R
R
P
T
K
K
P
R
T
P
R
Rat
Rattus norvegicus
XP_343484
893
96688
T448
T
T
T
T
R
R
P
T
K
K
P
R
T
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509725
896
98376
R449
S
T
T
T
T
T
R
R
P
T
K
K
P
R
T
Chicken
Gallus gallus
NP_001091009
896
97593
P449
S
T
A
T
T
R
R
P
T
R
R
P
K
T
P
Frog
Xenopus laevis
NP_001082480
886
97556
R446
T
T
T
K
K
P
T
R
K
P
R
T
R
P
P
Zebra Danio
Brachydanio rerio
NP_775381
866
94555
R459
T
T
T
K
P
P
R
R
S
T
P
A
V
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392358
704
79379
D327
Q
G
I
G
Q
C
E
D
M
S
R
P
E
V
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786589
869
94279
T439
V
D
T
M
A
P
T
T
V
V
I
M
P
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
N.A.
N.A.
93.1
92.6
N.A.
85.4
77.7
68.9
60.8
N.A.
N.A.
20.6
N.A.
30
Protein Similarity:
100
99.4
98
N.A.
N.A.
95.8
95.3
N.A.
91.8
87.3
81
73.5
N.A.
N.A.
38.3
N.A.
48.7
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
20
20
33.3
26.6
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
33.3
33.3
40
26.6
N.A.
N.A.
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
10
0
0
10
0
% I
% Lys:
0
0
0
19
10
0
0
0
55
46
10
10
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
10
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
28
46
10
10
10
55
19
19
55
37
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
46
55
28
28
0
10
28
46
10
10
46
% R
% Ser:
19
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% S
% Thr:
64
82
82
64
19
10
19
55
10
19
0
10
46
19
10
% T
% Val:
10
0
0
0
0
0
0
0
10
10
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _