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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAG1 All Species: 18.48
Human Site: T463 Identified Species: 40.67
UniProt: Q14118 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14118 NP_004384.2 895 97441 T463 P R P V P R V T T K V S I T R
Chimpanzee Pan troglodytes XP_001164638 895 97501 T463 P R P V P R V T T K V P I T R
Rhesus Macaque Macaca mulatta XP_001108323 894 97378 T462 P R P V P R V T T K V P I T R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q62165 893 96886 T461 P R P V P R V T T K A P I T R
Rat Rattus norvegicus XP_343484 893 96688 T461 P R P V P R V T T K A P I T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509725 896 98376 R462 R T P R P P P R V T T K A P I
Chicken Gallus gallus NP_001091009 896 97593 P462 T P R P T K P P S T T R S T I
Frog Xenopus laevis NP_001082480 886 97556 T459 P P K P L A T T K A P A T K F
Zebra Danio Brachydanio rerio NP_775381 866 94555 P472 I G D S N I K P E L R N P I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392358 704 79379 E340 V P K V S T Q E P K S N F P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786589 869 94279 T452 T P T K P V T T P S D T I P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.4 N.A. N.A. 93.1 92.6 N.A. 85.4 77.7 68.9 60.8 N.A. N.A. 20.6 N.A. 30
Protein Similarity: 100 99.4 98 N.A. N.A. 95.8 95.3 N.A. 91.8 87.3 81 73.5 N.A. N.A. 38.3 N.A. 48.7
P-Site Identity: 100 93.3 93.3 N.A. N.A. 86.6 86.6 N.A. 13.3 6.6 13.3 0 N.A. N.A. 13.3 N.A. 20
P-Site Similarity: 100 93.3 93.3 N.A. N.A. 86.6 86.6 N.A. 13.3 20 20 6.6 N.A. N.A. 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 10 19 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 10 0 0 0 0 0 0 55 10 19 % I
% Lys: 0 0 19 10 0 10 10 0 10 55 0 10 0 10 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 19 0 0 0 % N
% Pro: 55 37 55 19 64 10 19 19 19 0 10 37 10 28 10 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 10 46 10 10 0 46 0 10 0 0 10 10 0 0 46 % R
% Ser: 0 0 0 10 10 0 0 0 10 10 10 10 10 0 0 % S
% Thr: 19 10 10 0 10 10 19 64 46 19 19 10 10 55 0 % T
% Val: 10 0 0 55 0 10 46 0 10 0 28 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _