KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DAG1
All Species:
17.27
Human Site:
T464
Identified Species:
38
UniProt:
Q14118
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14118
NP_004384.2
895
97441
T464
R
P
V
P
R
V
T
T
K
V
S
I
T
R
L
Chimpanzee
Pan troglodytes
XP_001164638
895
97501
T464
R
P
V
P
R
V
T
T
K
V
P
I
T
R
L
Rhesus Macaque
Macaca mulatta
XP_001108323
894
97378
T463
R
P
V
P
R
V
T
T
K
V
P
I
T
R
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62165
893
96886
T462
R
P
V
P
R
V
T
T
K
A
P
I
T
R
L
Rat
Rattus norvegicus
XP_343484
893
96688
T462
R
P
V
P
R
V
T
T
K
A
P
I
T
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509725
896
98376
V463
T
P
R
P
P
P
R
V
T
T
K
A
P
I
T
Chicken
Gallus gallus
NP_001091009
896
97593
S463
P
R
P
T
K
P
P
S
T
T
R
S
T
I
S
Frog
Xenopus laevis
NP_001082480
886
97556
K460
P
K
P
L
A
T
T
K
A
P
A
T
K
F
E
Zebra Danio
Brachydanio rerio
NP_775381
866
94555
E473
G
D
S
N
I
K
P
E
L
R
N
P
I
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392358
704
79379
P341
P
K
V
S
T
Q
E
P
K
S
N
F
P
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786589
869
94279
P453
P
T
K
P
V
T
T
P
S
D
T
I
P
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
N.A.
N.A.
93.1
92.6
N.A.
85.4
77.7
68.9
60.8
N.A.
N.A.
20.6
N.A.
30
Protein Similarity:
100
99.4
98
N.A.
N.A.
95.8
95.3
N.A.
91.8
87.3
81
73.5
N.A.
N.A.
38.3
N.A.
48.7
P-Site Identity:
100
93.3
93.3
N.A.
N.A.
86.6
86.6
N.A.
13.3
6.6
6.6
0
N.A.
N.A.
20
N.A.
20
P-Site Similarity:
100
93.3
93.3
N.A.
N.A.
86.6
86.6
N.A.
13.3
20
13.3
6.6
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
10
19
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
10
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
10
10
0
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
55
10
19
0
% I
% Lys:
0
19
10
0
10
10
0
10
55
0
10
0
10
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
19
0
0
0
0
% N
% Pro:
37
55
19
64
10
19
19
19
0
10
37
10
28
10
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% Q
% Arg:
46
10
10
0
46
0
10
0
0
10
10
0
0
46
0
% R
% Ser:
0
0
10
10
0
0
0
10
10
10
10
10
0
0
10
% S
% Thr:
10
10
0
10
10
19
64
46
19
19
10
10
55
0
10
% T
% Val:
0
0
55
0
10
46
0
10
0
28
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _