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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGCR6
All Species:
17.88
Human Site:
S77
Identified Species:
39.33
UniProt:
Q14129
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14129
NP_005666.2
220
24989
S77
I
Q
H
L
T
E
K
S
L
Y
N
Q
R
L
R
Chimpanzee
Pan troglodytes
XP_001164365
220
24998
S77
I
Q
H
L
T
E
K
S
L
Y
N
Q
R
L
R
Rhesus Macaque
Macaca mulatta
XP_001082214
220
25077
S77
I
Q
H
F
T
E
K
S
L
Y
N
Q
R
L
R
Dog
Lupus familis
XP_849993
198
22605
S77
I
Q
H
L
T
E
K
S
L
Y
N
Q
R
L
R
Cat
Felis silvestris
Mouse
Mus musculus
NP_034177
170
19522
Q107
H
R
I
R
E
E
Q
Q
A
M
D
R
K
I
V
Rat
Rattus norvegicus
NP_001100550
198
22815
S77
I
Q
H
L
T
E
K
S
L
Y
N
Q
R
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990371
200
23224
N79
I
Q
H
L
T
E
K
N
L
Y
S
Q
R
L
K
Frog
Xenopus laevis
NP_001088026
198
23189
N77
I
Q
H
L
T
E
K
N
L
Y
N
Q
R
L
K
Zebra Danio
Brachydanio rerio
NP_991302
197
22674
N77
I
Q
H
L
T
E
K
N
L
Y
N
Q
R
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001027127
194
22635
H89
L
Q
H
E
T
E
R
H
L
I
K
I
R
M
Q
Honey Bee
Apis mellifera
XP_001123210
174
20215
L79
L
F
Q
Q
R
L
Q
L
L
N
Q
Q
K
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.8
85
N.A.
70
82.7
N.A.
N.A.
69.5
63.1
59.5
N.A.
34.5
37.2
N.A.
N.A.
Protein Similarity:
100
100
97.7
86.8
N.A.
74
87.2
N.A.
N.A.
79.5
75
74
N.A.
54
52.7
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
6.6
100
N.A.
N.A.
80
86.6
80
N.A.
40
13.3
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
46.6
100
N.A.
N.A.
100
100
93.3
N.A.
66.6
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
10
10
91
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
82
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
73
0
10
0
0
0
0
0
0
10
0
10
0
19
0
% I
% Lys:
0
0
0
0
0
0
73
0
0
0
10
0
19
0
28
% K
% Leu:
19
0
0
64
0
10
0
10
91
0
0
0
0
64
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
28
0
10
64
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
82
10
10
0
0
19
10
0
0
10
82
0
10
10
% Q
% Arg:
0
10
0
10
10
0
10
0
0
0
0
10
82
0
46
% R
% Ser:
0
0
0
0
0
0
0
46
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
82
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
73
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _