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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGCR6 All Species: 30.3
Human Site: Y79 Identified Species: 66.67
UniProt: Q14129 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14129 NP_005666.2 220 24989 Y79 H L T E K S L Y N Q R L R L Q
Chimpanzee Pan troglodytes XP_001164365 220 24998 Y79 H L T E K S L Y N Q R L R L Q
Rhesus Macaque Macaca mulatta XP_001082214 220 25077 Y79 H F T E K S L Y N Q R L R L Q
Dog Lupus familis XP_849993 198 22605 Y79 H L T E K S L Y N Q R L R L Q
Cat Felis silvestris
Mouse Mus musculus NP_034177 170 19522 M109 I R E E Q Q A M D R K I V L E
Rat Rattus norvegicus NP_001100550 198 22815 Y79 H L T E K S L Y N Q R L R L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_990371 200 23224 Y81 H L T E K N L Y S Q R L K L H
Frog Xenopus laevis NP_001088026 198 23189 Y79 H L T E K N L Y N Q R L K L H
Zebra Danio Brachydanio rerio NP_991302 197 22674 Y79 H L T E K N L Y N Q R Q K L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027127 194 22635 I91 H E T E R H L I K I R M Q A E
Honey Bee Apis mellifera XP_001123210 174 20215 N81 Q Q R L Q L L N Q Q K I E M Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.8 85 N.A. 70 82.7 N.A. N.A. 69.5 63.1 59.5 N.A. 34.5 37.2 N.A. N.A.
Protein Similarity: 100 100 97.7 86.8 N.A. 74 87.2 N.A. N.A. 79.5 75 74 N.A. 54 52.7 N.A. N.A.
P-Site Identity: 100 100 93.3 100 N.A. 13.3 100 N.A. N.A. 73.3 80 73.3 N.A. 33.3 20 N.A. N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 53.3 100 N.A. N.A. 93.3 93.3 86.6 N.A. 60 46.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 10 10 91 0 0 0 0 0 0 0 0 10 0 19 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 82 0 0 0 0 10 0 0 0 0 0 0 0 0 28 % H
% Ile: 10 0 0 0 0 0 0 10 0 10 0 19 0 0 0 % I
% Lys: 0 0 0 0 73 0 0 0 10 0 19 0 28 0 0 % K
% Leu: 0 64 0 10 0 10 91 0 0 0 0 64 0 82 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 10 0 10 0 % M
% Asn: 0 0 0 0 0 28 0 10 64 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 10 0 0 19 10 0 0 10 82 0 10 10 0 55 % Q
% Arg: 0 10 10 0 10 0 0 0 0 10 82 0 46 0 0 % R
% Ser: 0 0 0 0 0 46 0 0 10 0 0 0 0 0 0 % S
% Thr: 0 0 82 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 73 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _