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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BOP1 All Species: 20
Human Site: S349 Identified Species: 44
UniProt: Q14137 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14137 NP_056016.1 746 83630 S349 F L P R K F P S L R A V P A Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P97452 732 82527 S335 F L P Q K F P S L R T V P A Y
Rat Rattus norvegicus Q562C2 731 82621 S334 F L P Q K F P S L R T V P A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q7ZXX9 728 83447 C331 F L P Q R F N C L R A V P G Y
Zebra Danio Brachydanio rerio A0JMQ0 777 88347 C379 F L P Q K F S C L R A V P A F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K0Y1 784 90425 S383 F M P Q K F K S L R E V P A Y
Honey Bee Apis mellifera XP_623929 725 84096 S324 F I P Q K F N S L R E V P S Y
Nematode Worm Caenorhab. elegans Q9U2A9 674 77363 P316 K M R I H A D P T D L L P D L
Sea Urchin Strong. purpuratus XP_780573 808 93279 C409 F V P K K Y D C L R K V P Y Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04660 807 91686 A373 F I P Q K Y S A L R K V P G Y
Red Bread Mold Neurospora crassa Q7SEM3 779 87695 S368 Y L P Q K Y D S L R K V P G Y
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 83.3 83.5 N.A. N.A. N.A. 67.8 63.7 N.A. 48.5 46.5 43.5 51.4
Protein Similarity: 100 N.A. N.A. N.A. N.A. 89.8 89.5 N.A. N.A. N.A. 80 76.5 N.A. 67 68.9 59.1 68.5
P-Site Identity: 100 N.A. N.A. N.A. N.A. 86.6 86.6 N.A. N.A. N.A. 66.6 73.3 N.A. 73.3 66.6 6.6 53.3
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 93.3 93.3 N.A. N.A. N.A. 80 86.6 N.A. 86.6 86.6 20 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 38.2 38.3
Protein Similarity: N.A. N.A. N.A. N.A. 56.8 56.7
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 60
P-Site Similarity: N.A. N.A. N.A. N.A. 80 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 10 0 0 28 0 0 46 0 % A
% Cys: 0 0 0 0 0 0 0 28 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 28 0 0 10 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % E
% Phe: 82 0 0 0 0 64 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 19 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 10 82 0 10 0 0 0 28 0 0 0 0 % K
% Leu: 0 55 0 0 0 0 0 0 91 0 10 10 0 0 10 % L
% Met: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 91 0 0 0 28 10 0 0 0 0 100 0 0 % P
% Gln: 0 0 0 73 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 10 10 0 0 0 0 91 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 19 55 0 0 0 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 19 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 91 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 28 0 0 0 0 0 0 0 10 82 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _