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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE4A
All Species:
23.64
Human Site:
S620
Identified Species:
37.14
UniProt:
Q14139
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14139
NP_004779.2
1066
122561
S620
P
L
P
D
G
Y
S
S
L
A
Y
V
P
E
F
Chimpanzee
Pan troglodytes
XP_001161169
1066
122495
S620
P
L
P
D
G
Y
S
S
L
A
Y
V
P
E
F
Rhesus Macaque
Macaca mulatta
XP_001097812
1067
122494
S620
P
L
P
D
G
Y
S
S
L
A
Y
V
P
E
F
Dog
Lupus familis
XP_850081
1066
122542
S620
P
L
P
D
G
Y
S
S
L
A
Y
V
P
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES00
1173
133285
K746
P
L
N
S
E
V
P
K
V
F
A
A
L
P
E
Rat
Rattus norvegicus
Q6P7A2
1066
122361
S620
P
L
P
D
G
Y
S
S
L
A
Y
V
P
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026081
1074
123247
S623
P
L
P
G
V
E
N
S
A
L
A
Y
V
P
E
Frog
Xenopus laevis
NP_001084506
1072
122544
S621
P
V
P
N
I
Q
H
S
A
L
A
Y
V
P
E
Zebra Danio
Brachydanio rerio
XP_001922961
1078
122949
S627
P
L
P
S
L
E
N
S
L
L
C
Y
V
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609060
993
113046
I560
Q
S
V
P
E
S
I
I
D
N
I
S
A
F
L
Honey Bee
Apis mellifera
XP_393070
965
109934
T540
P
K
E
C
K
V
V
T
F
P
L
P
E
T
V
Nematode Worm
Caenorhab. elegans
Q09349
980
113212
M564
L
P
T
E
V
S
Q
M
F
C
A
L
P
E
Y
Sea Urchin
Strong. purpuratus
XP_786748
942
107668
M560
L
E
P
Q
F
L
E
M
A
F
N
L
H
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LF41
1038
117510
D596
M
P
E
H
F
V
E
D
A
M
E
L
L
I
F
Baker's Yeast
Sacchar. cerevisiae
P54860
961
109887
L539
E
G
P
V
N
Y
S
L
Y
I
S
K
Y
Q
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
98.6
N.A.
24.6
97
N.A.
N.A.
87.7
79.7
76.7
N.A.
33.1
36.5
22.9
32.7
Protein Similarity:
100
100
98.5
99.4
N.A.
45.2
99
N.A.
N.A.
94.3
90.8
87.4
N.A.
51.3
54.5
42.5
52.2
P-Site Identity:
100
100
100
100
N.A.
13.3
100
N.A.
N.A.
26.6
20
33.3
N.A.
0
6.6
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
N.A.
33.3
33.3
40
N.A.
0
13.3
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
27
34
27
7
7
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
7
7
0
0
0
0
% C
% Asp:
0
0
0
34
0
0
0
7
7
0
0
0
0
0
0
% D
% Glu:
7
7
14
7
14
14
14
0
0
0
7
0
7
40
27
% E
% Phe:
0
0
0
0
14
0
0
0
14
14
0
0
0
7
40
% F
% Gly:
0
7
0
7
34
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
7
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
7
0
7
7
0
7
7
0
0
14
0
% I
% Lys:
0
7
0
0
7
0
0
7
0
0
0
7
0
0
0
% K
% Leu:
14
54
0
0
7
7
0
7
40
20
7
20
14
0
7
% L
% Met:
7
0
0
0
0
0
0
14
0
7
0
0
0
0
0
% M
% Asn:
0
0
7
7
7
0
14
0
0
7
7
0
0
0
0
% N
% Pro:
67
14
67
7
0
0
7
0
0
7
0
7
40
27
0
% P
% Gln:
7
0
0
7
0
7
7
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
14
0
14
40
54
0
0
7
7
0
0
0
% S
% Thr:
0
0
7
0
0
0
0
7
0
0
0
0
0
7
7
% T
% Val:
0
7
7
7
14
20
7
0
7
0
0
34
20
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
40
0
0
7
0
34
20
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _