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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE4A All Species: 40.61
Human Site: S938 Identified Species: 63.81
UniProt: Q14139 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14139 NP_004779.2 1066 122561 S938 T V P K D G R S Y S P T L F A
Chimpanzee Pan troglodytes XP_001161169 1066 122495 S938 T V P K D G R S Y S P T L F A
Rhesus Macaque Macaca mulatta XP_001097812 1067 122494 S938 T V P K D G R S Y S P T L F A
Dog Lupus familis XP_850081 1066 122542 S938 T V P K D G R S Y S P T L F A
Cat Felis silvestris
Mouse Mus musculus Q9ES00 1173 133285 Y1049 I A D D Q R S Y S K E L F E E
Rat Rattus norvegicus Q6P7A2 1066 122361 S938 T V P K D G R S Y S P T L F A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026081 1074 123247 S942 T V P K D G R S Y S P T L F A
Frog Xenopus laevis NP_001084506 1072 122544 S940 S V P K D G R S Y S P M L F A
Zebra Danio Brachydanio rerio XP_001922961 1078 122949 S947 T V P K D G R S Y S P T L F C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609060 993 113046 S866 A V S Q D G R S Y S E Q L F S
Honey Bee Apis mellifera XP_393070 965 109934 S837 A V S Q D G R S Y S S E L F K
Nematode Worm Caenorhab. elegans Q09349 980 113212 Y856 I A Y D E R T Y S P E F F H N
Sea Urchin Strong. purpuratus XP_786748 942 107668 P825 P F H G F Q Q P L T Y Q G Y D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LF41 1038 117510 D888 F P G A I S S D G R S Y N E Q
Baker's Yeast Sacchar. cerevisiae P54860 961 109887 S829 A V A K D E R S F N R N L F V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.1 98.6 N.A. 24.6 97 N.A. N.A. 87.7 79.7 76.7 N.A. 33.1 36.5 22.9 32.7
Protein Similarity: 100 100 98.5 99.4 N.A. 45.2 99 N.A. N.A. 94.3 90.8 87.4 N.A. 51.3 54.5 42.5 52.2
P-Site Identity: 100 100 100 100 N.A. 0 100 N.A. N.A. 100 86.6 93.3 N.A. 60 60 0 0
P-Site Similarity: 100 100 100 100 N.A. 0 100 N.A. N.A. 100 93.3 93.3 N.A. 73.3 66.6 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. 25.3 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 43.9 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 14 7 7 0 0 0 0 0 0 0 0 0 0 47 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 7 14 74 0 0 7 0 0 0 0 0 0 7 % D
% Glu: 0 0 0 0 7 7 0 0 0 0 20 7 0 14 7 % E
% Phe: 7 7 0 0 7 0 0 0 7 0 0 7 14 74 0 % F
% Gly: 0 0 7 7 0 67 0 0 7 0 0 0 7 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 14 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 60 0 0 0 0 0 7 0 0 0 0 7 % K
% Leu: 0 0 0 0 0 0 0 0 7 0 0 7 74 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 0 7 7 0 7 % N
% Pro: 7 7 54 0 0 0 0 7 0 7 54 0 0 0 0 % P
% Gln: 0 0 0 14 7 7 7 0 0 0 0 14 0 0 7 % Q
% Arg: 0 0 0 0 0 14 74 0 0 7 7 0 0 0 0 % R
% Ser: 7 0 14 0 0 7 14 74 14 67 14 0 0 0 7 % S
% Thr: 47 0 0 0 0 0 7 0 0 7 0 47 0 0 0 % T
% Val: 0 74 0 0 0 0 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 14 67 0 7 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _