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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE4A
All Species:
17.27
Human Site:
T1045
Identified Species:
27.14
UniProt:
Q14139
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14139
NP_004779.2
1066
122561
T1045
M
D
Q
I
R
P
N
T
E
L
K
E
K
I
Q
Chimpanzee
Pan troglodytes
XP_001161169
1066
122495
T1045
M
D
Q
I
R
P
N
T
E
L
K
E
K
I
Q
Rhesus Macaque
Macaca mulatta
XP_001097812
1067
122494
N1045
T
M
D
Q
I
R
P
N
T
E
L
K
E
K
I
Dog
Lupus familis
XP_850081
1066
122542
T1045
M
D
Q
I
R
P
N
T
E
L
K
E
K
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES00
1173
133285
E1156
S
M
L
E
P
V
P
E
L
K
E
Q
I
Q
A
Rat
Rattus norvegicus
Q6P7A2
1066
122361
T1045
M
D
Q
I
R
P
N
T
E
L
K
E
K
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026081
1074
123247
R1049
M
D
Q
I
R
P
N
R
E
L
K
E
K
I
Q
Frog
Xenopus laevis
NP_001084506
1072
122544
V1047
M
D
Q
I
K
P
N
V
E
V
K
D
R
I
L
Zebra Danio
Brachydanio rerio
XP_001922961
1078
122949
E1054
M
D
Q
I
R
P
N
E
E
L
R
Q
Q
I
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609060
993
113046
E972
M
D
K
V
K
S
N
E
A
L
K
Q
E
I
E
Honey Bee
Apis mellifera
XP_393070
965
109934
I943
M
D
M
V
K
S
N
I
E
L
Q
H
R
V
Q
Nematode Worm
Caenorhab. elegans
Q09349
980
113212
S962
H
N
E
L
S
P
D
S
E
L
K
A
K
I
Q
Sea Urchin
Strong. purpuratus
XP_786748
942
107668
I929
T
K
G
D
E
E
Y
I
P
L
Q
L
R
I
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LF41
1038
117510
I998
S
D
M
L
I
P
D
I
E
L
K
A
K
I
D
Baker's Yeast
Sacchar. cerevisiae
P54860
961
109887
E938
L
E
D
V
T
P
N
E
E
L
R
Q
K
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
98.6
N.A.
24.6
97
N.A.
N.A.
87.7
79.7
76.7
N.A.
33.1
36.5
22.9
32.7
Protein Similarity:
100
100
98.5
99.4
N.A.
45.2
99
N.A.
N.A.
94.3
90.8
87.4
N.A.
51.3
54.5
42.5
52.2
P-Site Identity:
100
100
0
100
N.A.
0
100
N.A.
N.A.
93.3
60
66.6
N.A.
40
40
46.6
13.3
P-Site Similarity:
100
100
13.3
100
N.A.
13.3
100
N.A.
N.A.
93.3
86.6
86.6
N.A.
80
73.3
80
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
0
0
14
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
14
7
0
0
14
0
0
0
0
7
0
0
7
% D
% Glu:
0
7
7
7
7
7
0
27
74
7
7
34
14
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
47
14
0
0
20
0
0
0
0
7
80
7
% I
% Lys:
0
7
7
0
20
0
0
0
0
7
60
7
54
7
0
% K
% Leu:
7
0
7
14
0
0
0
0
7
80
7
7
0
0
14
% L
% Met:
60
14
14
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
7
0
0
0
0
67
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
67
14
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
47
7
0
0
0
0
0
0
14
27
7
7
47
% Q
% Arg:
0
0
0
0
40
7
0
7
0
0
14
0
20
0
0
% R
% Ser:
14
0
0
0
7
14
0
7
0
0
0
0
0
0
0
% S
% Thr:
14
0
0
0
7
0
0
27
7
0
0
0
0
0
0
% T
% Val:
0
0
0
20
0
7
0
7
0
7
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _