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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE4A All Species: 22.73
Human Site: T694 Identified Species: 35.71
UniProt: Q14139 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14139 NP_004779.2 1066 122561 T694 V M P H L D Q T P N P L V S S
Chimpanzee Pan troglodytes XP_001161169 1066 122495 T694 V M P H L D Q T P N P L V S S
Rhesus Macaque Macaca mulatta XP_001097812 1067 122494 T694 V M P H L D Q T P N P L V S S
Dog Lupus familis XP_850081 1066 122542 T694 V M P H L D Q T P N P L V S S
Cat Felis silvestris
Mouse Mus musculus Q9ES00 1173 133285 V808 L V A K L V E V M F M T N P S
Rat Rattus norvegicus Q6P7A2 1066 122361 T694 V M P H L D Q T P S P L V S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026081 1074 123247 A698 V M P H L D Q A Q N P L V S S
Frog Xenopus laevis NP_001084506 1072 122544 V696 V M P H L E Q V Q N P L I S S
Zebra Danio Brachydanio rerio XP_001922961 1078 122949 S703 M P H M E T L S P G A A Q P I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609060 993 113046 S622 A L E F L L P S R I M G S H R
Honey Bee Apis mellifera XP_393070 965 109934 S593 P T S D E T M S P V T P S L G
Nematode Worm Caenorhab. elegans Q09349 980 113212 V624 L V S K L V R V L S S I Q P P
Sea Urchin Strong. purpuratus XP_786748 942 107668 L614 A E N L V T Y L Q F L R R F A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LF41 1038 117510 S653 L N C W M P R S S S S S S A T
Baker's Yeast Sacchar. cerevisiae P54860 961 109887 M590 Q L L S V G A M P L T D N S P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.1 98.6 N.A. 24.6 97 N.A. N.A. 87.7 79.7 76.7 N.A. 33.1 36.5 22.9 32.7
Protein Similarity: 100 100 98.5 99.4 N.A. 45.2 99 N.A. N.A. 94.3 90.8 87.4 N.A. 51.3 54.5 42.5 52.2
P-Site Identity: 100 100 100 100 N.A. 13.3 93.3 N.A. N.A. 86.6 73.3 6.6 N.A. 6.6 6.6 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 33.3 100 N.A. N.A. 86.6 86.6 20 N.A. 20 13.3 40 13.3
Percent
Protein Identity: N.A. N.A. N.A. 25.3 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 43.9 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 7 0 0 0 7 7 0 0 7 7 0 7 7 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 40 0 0 0 0 0 7 0 0 0 % D
% Glu: 0 7 7 0 14 7 7 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 7 0 0 0 0 0 14 0 0 0 7 0 % F
% Gly: 0 0 0 0 0 7 0 0 0 7 0 7 0 0 7 % G
% His: 0 0 7 47 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 7 0 7 7 0 7 % I
% Lys: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 20 14 7 7 67 7 7 7 7 7 7 47 0 7 0 % L
% Met: 7 47 0 7 7 0 7 7 7 0 14 0 0 0 0 % M
% Asn: 0 7 7 0 0 0 0 0 0 40 0 0 14 0 0 % N
% Pro: 7 7 47 0 0 7 7 0 54 0 47 7 0 20 14 % P
% Gln: 7 0 0 0 0 0 47 0 20 0 0 0 14 0 0 % Q
% Arg: 0 0 0 0 0 0 14 0 7 0 0 7 7 0 7 % R
% Ser: 0 0 14 7 0 0 0 27 7 20 14 7 20 54 54 % S
% Thr: 0 7 0 0 0 20 0 34 0 0 14 7 0 0 7 % T
% Val: 47 14 0 0 14 14 0 20 0 7 0 0 40 0 0 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _