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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE4A
All Species:
26.67
Human Site:
Y504
Identified Species:
41.9
UniProt:
Q14139
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14139
NP_004779.2
1066
122561
Y504
E
P
K
F
P
Q
N
Y
N
L
V
T
E
N
L
Chimpanzee
Pan troglodytes
XP_001161169
1066
122495
Y504
E
P
K
F
P
Q
N
Y
N
L
V
T
E
N
L
Rhesus Macaque
Macaca mulatta
XP_001097812
1067
122494
Y504
E
P
K
F
P
Q
N
Y
N
L
V
T
E
N
L
Dog
Lupus familis
XP_850081
1066
122542
Y504
E
P
K
F
P
Q
N
Y
N
L
V
T
E
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES00
1173
133285
F629
P
K
F
P
T
E
C
F
F
L
T
L
H
A
H
Rat
Rattus norvegicus
Q6P7A2
1066
122361
Y504
E
P
V
F
P
Q
S
Y
N
L
V
T
E
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026081
1074
123247
Y507
E
P
E
F
A
N
S
Y
N
L
V
T
E
N
L
Frog
Xenopus laevis
NP_001084506
1072
122544
F505
Q
P
D
F
P
E
N
F
N
L
V
T
E
N
L
Zebra Danio
Brachydanio rerio
XP_001922961
1078
122949
Y511
T
V
E
F
A
Q
S
Y
S
L
L
T
E
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609060
993
113046
E458
N
T
Q
M
A
Y
G
E
I
V
N
S
D
P
N
Honey Bee
Apis mellifera
XP_393070
965
109934
H434
T
E
C
F
F
L
T
H
R
A
L
D
L
G
Y
Nematode Worm
Caenorhab. elegans
Q09349
980
113212
I463
I
P
P
L
M
N
Q
I
S
E
Y
S
R
H
L
Sea Urchin
Strong. purpuratus
XP_786748
942
107668
M459
G
L
P
K
E
T
R
M
L
H
R
E
G
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LF41
1038
117510
F492
L
L
K
A
L
S
D
F
K
H
L
A
Q
D
I
Baker's Yeast
Sacchar. cerevisiae
P54860
961
109887
T436
D
V
F
A
R
F
I
T
A
Q
L
S
K
M
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
98.6
N.A.
24.6
97
N.A.
N.A.
87.7
79.7
76.7
N.A.
33.1
36.5
22.9
32.7
Protein Similarity:
100
100
98.5
99.4
N.A.
45.2
99
N.A.
N.A.
94.3
90.8
87.4
N.A.
51.3
54.5
42.5
52.2
P-Site Identity:
100
100
100
100
N.A.
6.6
86.6
N.A.
N.A.
73.3
73.3
53.3
N.A.
0
6.6
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
20
93.3
N.A.
N.A.
86.6
93.3
80
N.A.
26.6
20
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
20
0
0
0
7
7
0
7
0
7
0
% A
% Cys:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
0
7
0
0
0
0
7
7
7
0
% D
% Glu:
40
7
14
0
7
14
0
7
0
7
0
7
54
7
14
% E
% Phe:
0
0
14
60
7
7
0
20
7
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
7
0
0
0
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
14
0
0
7
7
7
% H
% Ile:
7
0
0
0
0
0
7
7
7
0
0
0
0
0
7
% I
% Lys:
0
7
34
7
0
0
0
0
7
0
0
0
7
0
0
% K
% Leu:
7
14
0
7
7
7
0
0
7
60
27
7
7
0
60
% L
% Met:
0
0
0
7
7
0
0
7
0
0
0
0
0
7
0
% M
% Asn:
7
0
0
0
0
14
34
0
47
0
7
0
0
54
7
% N
% Pro:
7
54
14
7
40
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
7
0
7
0
0
40
7
0
0
7
0
0
7
0
0
% Q
% Arg:
0
0
0
0
7
0
7
0
7
0
7
0
7
0
0
% R
% Ser:
0
0
0
0
0
7
20
0
14
0
0
20
0
0
0
% S
% Thr:
14
7
0
0
7
7
7
7
0
0
7
54
0
0
0
% T
% Val:
0
14
7
0
0
0
0
0
0
7
47
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
47
0
0
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _