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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT6
All Species:
32.12
Human Site:
S146
Identified Species:
64.24
UniProt:
Q14141
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14141
NP_055944.2
434
49717
S146
V
L
H
T
Y
H
D
S
R
I
H
V
C
L
Y
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
V155
R
Q
M
P
D
N
R
V
Q
C
C
L
Y
F
I
Rhesus Macaque
Macaca mulatta
XP_001082728
567
63604
S282
V
L
H
T
Y
H
D
S
R
I
H
V
C
L
Y
Dog
Lupus familis
XP_851778
434
49559
S146
V
L
H
T
Y
H
D
S
R
I
H
A
C
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1T4
434
49601
S146
V
L
H
S
Y
H
D
S
R
I
H
V
C
L
Y
Rat
Rattus norvegicus
B0BNF1
442
51234
T148
S
L
F
D
Y
H
D
T
R
I
H
V
C
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509765
539
60893
S251
V
L
H
S
Y
H
D
S
R
I
H
A
C
L
Y
Chicken
Gallus gallus
Q5ZMH1
349
40206
F125
I
Q
Y
I
D
N
Q
F
E
R
Y
L
H
D
E
Frog
Xenopus laevis
Q6IRQ5
427
49743
S146
S
L
F
N
Y
H
D
S
R
I
H
V
C
L
Y
Zebra Danio
Brachydanio rerio
Q642H3
420
48980
T146
S
L
F
N
Y
H
D
T
R
I
H
I
C
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54359
419
48456
S147
S
L
V
T
C
H
D
S
R
I
H
I
C
L
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32457
520
60021
K248
N
R
H
S
I
N
D
K
R
I
H
A
C
L
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
75.4
98.3
N.A.
96
74.2
N.A.
75.1
37
76.5
76.7
N.A.
66.1
N.A.
N.A.
N.A.
Protein Similarity:
100
61.9
75.6
99.5
N.A.
98.1
84.1
N.A.
77.7
55
86.6
86.6
N.A.
79.9
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
93.3
73.3
N.A.
86.6
0
80
66.6
N.A.
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
100
80
N.A.
93.3
33.3
80
80
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
9
9
0
84
0
0
% C
% Asp:
0
0
0
9
17
0
84
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% E
% Phe:
0
0
25
0
0
0
0
9
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
50
0
0
75
0
0
0
0
84
0
9
0
0
% H
% Ile:
9
0
0
9
9
0
0
0
0
84
0
17
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
75
0
0
0
0
0
0
0
0
0
17
0
84
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
17
0
25
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
0
0
0
9
0
9
0
0
0
0
0
0
% Q
% Arg:
9
9
0
0
0
0
9
0
84
9
0
0
0
0
0
% R
% Ser:
34
0
0
25
0
0
0
59
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
34
0
0
0
17
0
0
0
0
0
0
0
% T
% Val:
42
0
9
0
0
0
0
9
0
0
0
42
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
67
0
0
0
0
0
9
0
9
0
84
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _