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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPT6 All Species: 35.45
Human Site: S164 Identified Species: 70.91
UniProt: Q14141 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14141 NP_055944.2 434 49717 S164 P T G H S L K S L D L V T M K
Chimpanzee Pan troglodytes Q5R1W1 434 50272 D173 G H G L K P L D I E F M K R L
Rhesus Macaque Macaca mulatta XP_001082728 567 63604 S300 P T G H S L K S L D L V T M K
Dog Lupus familis XP_851778 434 49559 S164 P T G H S L K S L D L V T M K
Cat Felis silvestris
Mouse Mus musculus Q9R1T4 434 49601 S164 P T G H S L K S L D L V T M K
Rat Rattus norvegicus B0BNF1 442 51234 S166 P T G H S L K S L D L V T M K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509765 539 60893 S269 P T G H S L K S L D L V T M K
Chicken Gallus gallus Q5ZMH1 349 40206 N143 N R R H I I D N R V H C C F Y
Frog Xenopus laevis Q6IRQ5 427 49743 S164 P T G H S L K S L D L V A M K
Zebra Danio Brachydanio rerio Q642H3 420 48980 S164 P T G H S L K S L D L V T M K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54359 419 48456 S165 P T G H G L K S L D L V C M K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32457 520 60021 P266 P T G H Y L K P L D L K F M Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40 75.4 98.3 N.A. 96 74.2 N.A. 75.1 37 76.5 76.7 N.A. 66.1 N.A. N.A. N.A.
Protein Similarity: 100 61.9 75.6 99.5 N.A. 98.1 84.1 N.A. 77.7 55 86.6 86.6 N.A. 79.9 N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 100 6.6 93.3 100 N.A. 86.6 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 100 20 93.3 100 N.A. 86.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 17 0 0 % C
% Asp: 0 0 0 0 0 0 9 9 0 84 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 9 9 0 % F
% Gly: 9 0 92 0 9 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 9 0 92 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 9 9 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 9 0 84 0 0 0 0 9 9 0 75 % K
% Leu: 0 0 0 9 0 84 9 0 84 0 84 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 84 0 % M
% Asn: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 84 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 9 9 0 0 0 0 0 9 0 0 0 0 9 0 % R
% Ser: 0 0 0 0 67 0 0 75 0 0 0 0 0 0 0 % S
% Thr: 0 84 0 0 0 0 0 0 0 0 0 0 59 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 9 0 75 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _