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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT6
All Species:
41.82
Human Site:
T290
Identified Species:
83.64
UniProt:
Q14141
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14141
NP_055944.2
434
49717
T290
M
E
D
L
R
E
Q
T
H
T
R
H
Y
E
L
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
T298
M
Q
D
L
K
D
V
T
N
N
V
H
Y
E
N
Rhesus Macaque
Macaca mulatta
XP_001082728
567
63604
T426
M
E
D
L
R
E
Q
T
H
T
R
H
Y
E
L
Dog
Lupus familis
XP_851778
434
49559
T290
M
D
D
L
R
E
Q
T
H
S
R
H
Y
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1T4
434
49601
T290
M
E
D
L
R
E
Q
T
H
A
R
H
Y
E
L
Rat
Rattus norvegicus
B0BNF1
442
51234
T292
M
E
D
L
R
E
Q
T
H
S
R
H
Y
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509765
539
60893
T395
M
E
D
L
R
E
Q
T
H
A
R
H
Y
E
L
Chicken
Gallus gallus
Q5ZMH1
349
40206
G254
V
K
G
K
K
I
R
G
R
L
Y
P
W
G
V
Frog
Xenopus laevis
Q6IRQ5
427
49743
T290
M
E
D
L
R
E
Q
T
H
T
R
H
Y
E
L
Zebra Danio
Brachydanio rerio
Q642H3
420
48980
T290
M
E
D
L
R
E
Q
T
H
A
R
H
Y
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54359
419
48456
T291
M
E
D
M
R
E
K
T
H
T
R
H
Y
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32457
520
60021
T396
M
E
E
L
K
E
R
T
S
K
I
L
Y
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
75.4
98.3
N.A.
96
74.2
N.A.
75.1
37
76.5
76.7
N.A.
66.1
N.A.
N.A.
N.A.
Protein Similarity:
100
61.9
75.6
99.5
N.A.
98.1
84.1
N.A.
77.7
55
86.6
86.6
N.A.
79.9
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
100
86.6
N.A.
93.3
93.3
N.A.
93.3
0
100
93.3
N.A.
86.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
93.3
100
N.A.
93.3
40
100
93.3
N.A.
100
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
84
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
75
9
0
0
84
0
0
0
0
0
0
0
92
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
9
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
75
0
0
84
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
9
0
9
25
0
9
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
84
0
0
0
0
0
9
0
9
0
0
75
% L
% Met:
92
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
17
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
9
0
0
0
0
67
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
75
0
17
0
9
0
75
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
9
17
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
92
0
34
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
9
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
92
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _