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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KEAP1
All Species:
18.18
Human Site:
S73
Identified Species:
33.33
UniProt:
Q14145
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14145
NP_036421.2
624
69666
S73
I
M
N
E
L
R
L
S
Q
Q
L
C
D
V
T
Chimpanzee
Pan troglodytes
XP_512371
992
106974
S441
I
M
N
E
L
R
L
S
Q
Q
L
C
D
V
T
Rhesus Macaque
Macaca mulatta
XP_001105867
525
58783
Dog
Lupus familis
XP_533917
624
69690
S73
I
M
N
E
L
R
L
S
Q
Q
L
C
D
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2X8
624
69534
S73
V
M
N
E
L
R
L
S
Q
Q
L
C
D
V
T
Rat
Rattus norvegicus
P57790
624
69380
S73
I
M
N
E
L
R
L
S
Q
Q
L
C
D
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
G75
E
G
S
V
L
T
K
G
C
W
L
A
N
P
G
Chicken
Gallus gallus
Q5ZI33
586
66177
R53
V
I
L
M
V
Q
E
R
R
I
P
A
H
R
V
Frog
Xenopus laevis
Q6NRH0
564
63190
V31
K
S
Q
T
L
C
D
V
T
L
R
V
N
L
K
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
I31
K
S
N
T
L
C
D
I
T
L
R
V
E
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732202
776
87372
K74
F
C
M
S
N
Y
A
K
E
A
L
K
M
M
Y
Honey Bee
Apis mellifera
XP_395147
616
69734
L75
H
M
L
T
D
V
I
L
E
V
E
S
E
L
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788744
1147
128850
V254
L
D
R
K
L
G
K
V
Q
S
D
Q
Q
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.9
73.7
97.5
N.A.
94
93.7
N.A.
34.6
29.1
35.2
34.7
N.A.
37.5
47.9
N.A.
30.7
Protein Similarity:
100
62.9
76.9
98.5
N.A.
97.2
96.9
N.A.
50.2
47.5
50.9
51.1
N.A.
50.9
64
N.A.
40
P-Site Identity:
100
100
0
100
N.A.
93.3
100
N.A.
13.3
0
6.6
20
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
26.6
33.3
20
26.6
N.A.
20
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
0
16
0
0
0
% A
% Cys:
0
8
0
0
0
16
0
0
8
0
0
39
0
0
0
% C
% Asp:
0
8
0
0
8
0
16
0
0
0
8
0
39
0
0
% D
% Glu:
8
0
0
39
0
0
8
0
16
0
8
0
16
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
8
0
8
0
0
0
0
0
8
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
31
8
0
0
0
0
8
8
0
8
0
0
0
0
0
% I
% Lys:
16
0
0
8
0
0
16
8
0
0
0
8
0
0
8
% K
% Leu:
8
0
16
0
70
0
39
8
0
16
54
0
0
24
0
% L
% Met:
0
47
8
8
0
0
0
0
0
0
0
0
8
8
0
% M
% Asn:
0
0
47
0
8
0
0
0
0
0
0
0
16
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% P
% Gln:
0
0
8
0
0
8
0
0
47
39
0
8
8
0
0
% Q
% Arg:
0
0
8
0
0
39
0
8
8
0
16
0
0
8
0
% R
% Ser:
0
16
8
8
0
0
0
39
0
8
0
8
0
0
0
% S
% Thr:
0
0
0
24
0
8
0
0
16
0
0
0
0
0
47
% T
% Val:
16
0
0
8
8
8
0
16
0
8
0
16
0
39
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _