KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KEAP1
All Species:
16.06
Human Site:
S8
Identified Species:
29.44
UniProt:
Q14145
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14145
NP_036421.2
624
69666
S8
M
Q
P
D
P
R
P
S
G
A
G
A
C
C
R
Chimpanzee
Pan troglodytes
XP_512371
992
106974
S376
M
Q
P
D
P
R
P
S
G
A
G
A
C
C
R
Rhesus Macaque
Macaca mulatta
XP_001105867
525
58783
Dog
Lupus familis
XP_533917
624
69690
S8
M
Q
P
E
P
G
P
S
G
A
G
A
R
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2X8
624
69534
S8
M
Q
P
E
P
K
L
S
G
A
P
R
S
S
Q
Rat
Rattus norvegicus
P57790
624
69380
S8
M
Q
P
E
P
K
P
S
G
A
P
R
S
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
S10
E
S
P
R
G
H
P
S
L
K
S
S
I
P
R
Chicken
Gallus gallus
Q5ZI33
586
66177
Frog
Xenopus laevis
Q6NRH0
564
63190
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732202
776
87372
M9
Q
T
Q
M
H
S
P
M
Q
Y
E
T
H
I
S
Honey Bee
Apis mellifera
XP_395147
616
69734
K10
E
E
D
C
Y
M
K
K
E
A
Q
G
S
F
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788744
1147
128850
G189
N
D
A
Y
N
S
E
G
A
L
A
M
L
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.9
73.7
97.5
N.A.
94
93.7
N.A.
34.6
29.1
35.2
34.7
N.A.
37.5
47.9
N.A.
30.7
Protein Similarity:
100
62.9
76.9
98.5
N.A.
97.2
96.9
N.A.
50.2
47.5
50.9
51.1
N.A.
50.9
64
N.A.
40
P-Site Identity:
100
100
0
73.3
N.A.
46.6
53.3
N.A.
26.6
0
0
0
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
0
80
N.A.
66.6
73.3
N.A.
33.3
0
0
0
N.A.
6.6
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
8
47
8
24
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
16
16
0
% C
% Asp:
0
8
8
16
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
16
8
0
24
0
0
8
0
8
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
8
8
0
8
39
0
24
8
0
0
0
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
0
0
0
16
8
8
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
8
8
0
0
8
0
0
% L
% Met:
39
0
0
8
0
8
0
8
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
47
0
39
0
47
0
0
0
16
0
0
8
0
% P
% Gln:
8
39
8
0
0
0
0
0
8
0
8
0
0
0
16
% Q
% Arg:
0
0
0
8
0
16
0
0
0
0
0
16
8
0
39
% R
% Ser:
0
8
0
0
0
16
0
47
0
0
8
8
24
16
8
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _