KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KEAP1
All Species:
31.52
Human Site:
Y396
Identified Species:
57.78
UniProt:
Q14145
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14145
NP_036421.2
624
69666
Y396
D
S
S
A
L
D
C
Y
N
P
M
T
N
Q
W
Chimpanzee
Pan troglodytes
XP_512371
992
106974
Y764
D
S
S
A
L
D
C
Y
N
P
M
T
N
Q
W
Rhesus Macaque
Macaca mulatta
XP_001105867
525
58783
D299
Q
S
D
S
R
C
K
D
Y
L
V
K
I
F
E
Dog
Lupus familis
XP_533917
624
69690
Y396
D
S
S
A
L
D
C
Y
N
P
M
T
N
Q
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2X8
624
69534
Y396
D
S
S
A
L
D
C
Y
N
P
M
T
N
Q
W
Rat
Rattus norvegicus
P57790
624
69380
Y396
D
S
S
A
L
D
C
Y
N
P
M
T
N
Q
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
Y451
A
I
S
S
V
E
R
Y
D
P
Q
T
N
E
W
Chicken
Gallus gallus
Q5ZI33
586
66177
D360
D
C
Y
N
V
V
K
D
S
W
Y
S
K
L
G
Frog
Xenopus laevis
Q6NRH0
564
63190
R338
G
G
Y
D
G
R
S
R
L
S
S
V
E
C
L
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
R338
G
G
Y
D
G
R
S
R
L
S
S
V
E
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732202
776
87372
Y403
D
S
D
W
V
D
R
Y
S
A
V
T
E
T
W
Honey Bee
Apis mellifera
XP_395147
616
69734
Y384
D
S
D
W
V
D
R
Y
N
P
L
T
D
Q
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788744
1147
128850
Y917
D
S
N
R
L
D
A
Y
N
P
L
N
N
Q
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.9
73.7
97.5
N.A.
94
93.7
N.A.
34.6
29.1
35.2
34.7
N.A.
37.5
47.9
N.A.
30.7
Protein Similarity:
100
62.9
76.9
98.5
N.A.
97.2
96.9
N.A.
50.2
47.5
50.9
51.1
N.A.
50.9
64
N.A.
40
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
40
6.6
0
0
N.A.
40
60
N.A.
66.6
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
73.3
26.6
0
0
N.A.
60
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
39
0
0
8
0
0
8
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
8
39
0
0
0
0
0
0
16
0
% C
% Asp:
70
0
24
16
0
62
0
16
8
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
24
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
16
16
0
0
16
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
16
0
0
0
0
8
8
0
0
% K
% Leu:
0
0
0
0
47
0
0
0
16
8
16
0
0
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
39
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
54
0
0
8
54
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
62
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
8
0
0
54
0
% Q
% Arg:
0
0
0
8
8
16
24
16
0
0
0
0
0
0
0
% R
% Ser:
0
70
47
16
0
0
16
0
16
16
16
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
62
0
8
0
% T
% Val:
0
0
0
0
31
8
0
0
0
0
16
16
0
0
0
% V
% Trp:
0
0
0
16
0
0
0
0
0
8
0
0
0
0
70
% W
% Tyr:
0
0
24
0
0
0
0
70
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _