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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX34
All Species:
7.88
Human Site:
S109
Identified Species:
19.26
UniProt:
Q14147
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14147
NP_055496.2
576
64567
S109
P
R
Y
R
I
N
L
S
V
L
G
P
A
T
R
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
R187
E
R
D
A
F
A
E
R
V
R
Q
R
D
K
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541537
1144
128600
S114
A
R
Y
R
I
N
L
S
V
L
G
P
D
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBV3
1145
128489
S111
P
R
Y
R
I
N
L
S
I
L
S
P
D
T
R
Rat
Rattus norvegicus
XP_001062397
1143
128333
I111
R
Y
R
I
N
L
S
I
L
G
P
D
T
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
A3KMI0
1362
153300
F308
S
L
E
D
H
P
L
F
N
P
A
V
K
I
P
Zebra Danio
Brachydanio rerio
NP_001121805
1150
130094
E109
S
V
C
S
R
D
I
E
E
R
L
A
G
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
R178
S
R
S
G
D
R
D
R
R
R
R
S
R
S
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
R146
D
R
D
R
D
R
N
R
D
R
D
D
R
R
D
Baker's Yeast
Sacchar. cerevisiae
P20095
876
99795
H159
A
M
A
G
Q
S
D
H
P
D
D
I
T
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.1
N.A.
46.8
N.A.
47
46.8
N.A.
N.A.
N.A.
20.4
34.4
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
100
36
N.A.
47.8
N.A.
48.4
48.3
N.A.
N.A.
N.A.
29
41.6
N.A.
N.A.
N.A.
32.2
N.A.
P-Site Identity:
100
13.3
N.A.
86.6
N.A.
80
0
N.A.
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
N.A.
86.6
N.A.
86.6
6.6
N.A.
N.A.
N.A.
6.6
20
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
39.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
10
10
0
10
0
0
0
0
10
10
10
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
20
10
20
10
20
0
10
10
20
20
30
0
30
% D
% Glu:
10
0
10
0
0
0
10
10
10
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
20
0
0
0
0
0
10
20
0
10
0
10
% G
% His:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
30
0
10
10
10
0
0
10
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% K
% Leu:
0
10
0
0
0
10
40
0
10
30
10
0
0
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
30
10
0
10
0
0
0
0
0
0
% N
% Pro:
20
0
0
0
0
10
0
0
10
10
10
30
0
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
10
60
10
40
10
20
0
30
10
40
10
10
20
20
40
% R
% Ser:
30
0
10
10
0
10
10
30
0
0
10
10
0
20
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
20
30
0
% T
% Val:
0
10
0
0
0
0
0
0
30
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
30
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _