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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX34
All Species:
13.33
Human Site:
S269
Identified Species:
32.59
UniProt:
Q14147
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14147
NP_055496.2
576
64567
S269
R
Q
I
Q
R
E
P
S
L
P
Q
Y
E
V
L
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
D513
R
E
F
L
S
E
P
D
L
A
S
Y
S
V
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541537
1144
128600
S273
R
Q
I
Q
R
E
P
S
L
P
Q
Y
Q
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBV3
1145
128489
S271
R
Q
I
Q
R
E
P
S
L
P
Q
Y
Q
V
L
Rat
Rattus norvegicus
XP_001062397
1143
128333
R270
R
Q
I
Q
C
E
P
R
L
P
Q
Y
Q
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
A3KMI0
1362
153300
T673
A
T
R
L
L
Y
C
T
T
G
I
L
L
R
K
Zebra Danio
Brachydanio rerio
NP_001121805
1150
130094
S269
R
Q
I
Q
Q
D
A
S
L
G
Q
Y
Q
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
D650
R
E
C
L
I
D
P
D
L
S
G
Y
S
L
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
N625
R
E
I
L
I
D
E
N
L
S
Q
Y
S
V
I
Baker's Yeast
Sacchar. cerevisiae
P20095
876
99795
E330
T
D
G
M
L
L
R
E
F
L
T
D
S
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.1
N.A.
46.8
N.A.
47
46.8
N.A.
N.A.
N.A.
20.4
34.4
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
100
36
N.A.
47.8
N.A.
48.4
48.3
N.A.
N.A.
N.A.
29
41.6
N.A.
N.A.
N.A.
32.2
N.A.
P-Site Identity:
100
40
N.A.
93.3
N.A.
93.3
80
N.A.
N.A.
N.A.
0
66.6
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
53.3
N.A.
100
N.A.
100
86.6
N.A.
N.A.
N.A.
6.6
86.6
N.A.
N.A.
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
39.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
10
0
10
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
30
0
20
0
0
0
10
0
0
0
% D
% Glu:
0
30
0
0
0
50
10
10
0
0
0
0
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
20
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
60
0
20
0
0
0
0
0
10
0
0
0
20
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% K
% Leu:
0
0
0
40
20
10
0
0
80
10
0
10
10
10
60
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
60
0
0
40
0
0
0
0
0
% P
% Gln:
0
50
0
50
10
0
0
0
0
0
60
0
40
0
0
% Q
% Arg:
80
0
10
0
30
0
10
10
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
10
0
0
40
0
20
10
0
40
0
0
% S
% Thr:
10
10
0
0
0
0
0
10
10
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
80
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _