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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX34
All Species:
17.88
Human Site:
S449
Identified Species:
43.7
UniProt:
Q14147
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14147
NP_055496.2
576
64567
S449
S
L
V
L
Q
M
K
S
M
S
V
G
D
P
R
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
K771
G
N
V
V
L
L
L
K
S
L
G
I
H
D
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541537
1144
128600
S538
A
L
V
L
Q
M
K
S
M
S
V
G
D
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBV3
1145
128489
S536
A
L
V
L
Q
M
K
S
M
S
V
G
D
P
R
Rat
Rattus norvegicus
XP_001062397
1143
128333
S535
A
L
V
L
Q
M
K
S
M
S
V
G
D
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
A3KMI0
1362
153300
K1019
E
L
C
L
H
I
M
K
C
D
L
G
S
P
E
Zebra Danio
Brachydanio rerio
NP_001121805
1150
130094
S534
S
L
I
L
Q
M
K
S
M
G
L
G
D
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
K908
A
S
T
L
L
Q
L
K
A
M
G
I
N
N
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
K883
G
M
T
T
L
T
M
K
A
M
G
I
N
D
L
Baker's Yeast
Sacchar. cerevisiae
P20095
876
99795
L595
S
N
T
V
L
L
L
L
S
L
G
V
T
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.1
N.A.
46.8
N.A.
47
46.8
N.A.
N.A.
N.A.
20.4
34.4
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
100
36
N.A.
47.8
N.A.
48.4
48.3
N.A.
N.A.
N.A.
29
41.6
N.A.
N.A.
N.A.
32.2
N.A.
P-Site Identity:
100
6.6
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
26.6
80
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
20
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
40
93.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
39.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
50
30
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
0
0
0
0
0
0
10
40
60
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
30
0
0
0
% I
% Lys:
0
0
0
0
0
0
50
40
0
0
0
0
0
0
0
% K
% Leu:
0
60
0
70
40
20
30
10
0
20
20
0
0
0
40
% L
% Met:
0
10
0
0
0
50
20
0
50
20
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
0
0
0
0
0
0
20
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% P
% Gln:
0
0
0
0
50
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% R
% Ser:
30
10
0
0
0
0
0
50
20
40
0
0
10
0
0
% S
% Thr:
0
0
30
10
0
10
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
50
20
0
0
0
0
0
0
40
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _