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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX34 All Species: 18.79
Human Site: S536 Identified Species: 45.93
UniProt: Q14147 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14147 NP_055496.2 576 64567 S536 V Q S P F T R S A Q S S P E C
Chimpanzee Pan troglodytes Q7YR39 1044 119631 R859 V N N S I F Y R P K D K V V H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541537 1144 128600 S625 V Q S P F T R S A Q S N P E C
Cat Felis silvestris
Mouse Mus musculus Q9DBV3 1145 128489 S623 V Q S P F T R S A Q S N L D C
Rat Rattus norvegicus XP_001062397 1143 128333 S622 V Q S P F T R S A Q S N L D C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis A3KMI0 1362 153300 P1109 E K S P F V T P I G E K D R A
Zebra Danio Brachydanio rerio NP_001121805 1150 130094 S621 V Q S P F L R S A Q H N P D C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09530 1200 135741 P996 V Q N I F Y R P K E K Q D H A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 S1021 E N F I Q S R S L R R A Q D V
Baker's Yeast Sacchar. cerevisiae P20095 876 99795 F719 N Q W R N S K F S R S W C Q D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.1 N.A. 46.8 N.A. 47 46.8 N.A. N.A. N.A. 20.4 34.4 N.A. N.A. N.A. 22.2 N.A.
Protein Similarity: 100 36 N.A. 47.8 N.A. 48.4 48.3 N.A. N.A. N.A. 29 41.6 N.A. N.A. N.A. 32.2 N.A.
P-Site Identity: 100 6.6 N.A. 93.3 N.A. 80 80 N.A. N.A. N.A. 20 73.3 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 100 20 N.A. 100 N.A. 93.3 93.3 N.A. N.A. N.A. 26.6 86.6 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.5 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. 33.9 39.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 50 0 0 10 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 50 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 20 40 10 % D
% Glu: 20 0 0 0 0 0 0 0 0 10 10 0 0 20 0 % E
% Phe: 0 0 10 0 70 10 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 10 % H
% Ile: 0 0 0 20 10 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 10 0 10 10 10 20 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 0 10 0 0 0 20 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 20 20 0 10 0 0 0 0 0 0 40 0 0 0 % N
% Pro: 0 0 0 60 0 0 0 20 10 0 0 0 30 0 0 % P
% Gln: 0 70 0 0 10 0 0 0 0 50 0 10 10 10 0 % Q
% Arg: 0 0 0 10 0 0 70 10 0 20 10 0 0 10 0 % R
% Ser: 0 0 60 10 0 20 0 60 10 0 50 10 0 0 0 % S
% Thr: 0 0 0 0 0 40 10 0 0 0 0 0 0 0 0 % T
% Val: 70 0 0 0 0 10 0 0 0 0 0 0 10 10 10 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _