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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3A
All Species:
30.3
Human Site:
S1059
Identified Species:
39.22
UniProt:
Q14152
Number Species:
17
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14152
NP_003741.1
1382
166569
S1059
G
A
D
D
E
R
S
S
W
R
N
A
D
D
D
Chimpanzee
Pan troglodytes
XP_001153575
1382
166541
S1059
G
A
D
D
E
R
S
S
W
R
N
A
D
D
D
Rhesus Macaque
Macaca mulatta
XP_001102472
1228
147070
S895
G
A
D
E
E
R
S
S
W
R
N
A
D
D
D
Dog
Lupus familis
XP_852131
1350
163016
S1059
G
A
D
D
E
R
S
S
W
R
N
A
D
D
D
Cat
Felis silvestris
Mouse
Mus musculus
P23116
1344
161918
S1059
G
A
D
D
E
R
S
S
W
R
N
A
D
D
D
Rat
Rattus norvegicus
Q1JU68
1354
163177
S1069
G
A
D
D
E
R
S
S
W
R
N
A
D
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514639
1362
163866
S1080
G
M
E
E
E
R
S
S
W
R
N
T
E
E
D
Chicken
Gallus gallus
XP_421787
1505
177889
S1144
G
L
D
D
D
R
G
S
W
R
A
A
D
D
D
Frog
Xenopus laevis
A2VD00
1424
168482
P1089
G
F
D
E
D
R
G
P
R
R
D
F
D
E
D
Zebra Danio
Brachydanio rerio
Q6PCR7
1267
151273
P1029
R
S
D
D
D
R
G
P
R
R
G
F
D
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN25
1140
133861
G954
G
E
R
I
E
R
G
G
D
R
D
R
K
D
N
Honey Bee
Apis mellifera
XP_397439
1143
134949
N969
D
K
D
D
T
R
D
N
R
D
R
I
D
K
D
Nematode Worm
Caenorhab. elegans
P34339
1076
124390
F895
P
T
R
E
P
R
E
F
R
G
D
R
D
R
E
Sea Urchin
Strong. purpuratus
XP_798957
1284
149812
R992
E
A
A
E
E
A
T
R
A
Q
P
S
R
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XHR2
962
111545
E803
Q
R
I
E
M
L
R
E
E
E
E
A
R
K
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD55
987
114281
V825
E
A
E
R
L
K
K
V
E
A
E
R
K
A
N
Baker's Yeast
Sacchar. cerevisiae
P38249
964
110326
A802
T
K
E
S
E
L
A
A
I
R
N
Q
K
K
A
Red Bread Mold
Neurospora crassa
Q7RWT1
1007
114509
A851
K
A
E
K
E
K
L
A
A
T
P
S
A
Y
R
Conservation
Percent
Protein Identity:
100
99.9
86.5
94.2
N.A.
93.1
93.1
N.A.
88.2
75.6
72.1
75
N.A.
41.5
42.1
31.4
45.4
Protein Similarity:
100
99.9
87.4
95.9
N.A.
95.5
95.5
N.A.
93.1
81.7
81.4
82.1
N.A.
58
58.5
48.3
62.1
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
60
73.3
40
46.6
N.A.
33.3
33.3
13.3
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
80
66.6
60
N.A.
46.6
40
33.3
53.3
Percent
Protein Identity:
N.A.
27.2
N.A.
27.1
23.3
28.2
Protein Similarity:
N.A.
43.8
N.A.
44.6
41
43.6
P-Site Identity:
N.A.
6.6
N.A.
6.6
20
13.3
P-Site Similarity:
N.A.
13.3
N.A.
26.6
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
6
0
0
6
6
12
12
6
6
45
6
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
56
45
17
0
6
0
6
6
17
0
62
56
62
% D
% Glu:
12
6
23
34
62
0
6
6
12
6
12
0
6
12
12
% E
% Phe:
0
6
0
0
0
0
0
6
0
0
0
12
0
0
0
% F
% Gly:
56
0
0
0
0
0
23
6
0
6
6
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
6
0
0
0
0
6
0
0
6
0
0
0
% I
% Lys:
6
12
0
6
0
12
6
0
0
0
0
0
17
17
0
% K
% Leu:
0
6
0
0
6
12
6
0
0
0
0
0
0
0
0
% L
% Met:
0
6
0
0
6
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
6
0
0
45
0
0
0
12
% N
% Pro:
6
0
0
0
6
0
0
12
0
0
12
0
0
0
0
% P
% Gln:
6
0
0
0
0
0
0
0
0
6
0
6
0
0
0
% Q
% Arg:
6
6
12
6
0
73
6
6
23
67
6
17
12
6
12
% R
% Ser:
0
6
0
6
0
0
39
45
0
0
0
12
0
0
0
% S
% Thr:
6
6
0
0
6
0
6
0
0
6
0
6
0
0
0
% T
% Val:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
45
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _