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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3A
All Species:
22.73
Human Site:
S1198
Identified Species:
29.41
UniProt:
Q14152
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.12
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14152
NP_003741.1
1382
166569
S1198
P
P
R
E
S
R
P
S
E
E
R
E
W
D
R
Chimpanzee
Pan troglodytes
XP_001153575
1382
166541
S1198
P
P
R
E
S
R
P
S
E
E
R
E
W
D
R
Rhesus Macaque
Macaca mulatta
XP_001102472
1228
147070
S1044
P
P
R
E
S
R
P
S
E
E
R
E
W
D
R
Dog
Lupus familis
XP_852131
1350
163016
S1159
P
P
R
E
S
R
P
S
E
E
R
E
W
D
R
Cat
Felis silvestris
Mouse
Mus musculus
P23116
1344
161918
S1159
P
P
R
E
S
R
P
S
E
E
R
E
W
D
R
Rat
Rattus norvegicus
Q1JU68
1354
163177
P1169
P
P
R
E
S
R
P
P
E
E
R
E
W
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514639
1362
163866
S1188
P
P
R
E
S
R
P
S
E
D
R
D
W
D
R
Chicken
Gallus gallus
XP_421787
1505
177889
P1333
P
P
R
D
S
R
P
P
G
D
R
E
W
D
R
Frog
Xenopus laevis
A2VD00
1424
168482
P1296
P
S
H
D
S
K
P
P
E
E
R
D
W
S
K
Zebra Danio
Brachydanio rerio
Q6PCR7
1267
151273
D1118
P
P
R
D
S
G
H
D
D
D
G
G
E
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN25
1140
133861
R1027
R
D
R
D
D
G
P
R
R
D
R
D
D
E
R
Honey Bee
Apis mellifera
XP_397439
1143
134949
R1033
S
G
G
G
S
H
R
R
E
E
T
M
R
N
I
Nematode Worm
Caenorhab. elegans
P34339
1076
124390
A960
R
N
D
P
P
R
P
A
S
K
A
D
T
G
D
Sea Urchin
Strong. purpuratus
XP_798957
1284
149812
R1096
G
P
R
D
S
G
R
R
E
E
R
Y
G
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XHR2
962
111545
V859
L
L
K
G
S
E
A
V
R
A
P
D
S
A
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD55
987
114281
A883
P
V
G
T
T
A
P
A
A
A
A
A
A
A
G
Baker's Yeast
Sacchar. cerevisiae
P38249
964
110326
I860
A
T
R
K
Q
R
E
I
E
E
A
A
A
K
K
Red Bread Mold
Neurospora crassa
Q7RWT1
1007
114509
P906
P
A
P
A
A
A
E
P
V
A
E
R
P
R
A
Conservation
Percent
Protein Identity:
100
99.9
86.5
94.2
N.A.
93.1
93.1
N.A.
88.2
75.6
72.1
75
N.A.
41.5
42.1
31.4
45.4
Protein Similarity:
100
99.9
87.4
95.9
N.A.
95.5
95.5
N.A.
93.1
81.7
81.4
82.1
N.A.
58
58.5
48.3
62.1
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
86.6
73.3
46.6
26.6
N.A.
26.6
20
13.3
40
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
100
86.6
73.3
46.6
N.A.
53.3
26.6
33.3
53.3
Percent
Protein Identity:
N.A.
27.2
N.A.
27.1
23.3
28.2
Protein Similarity:
N.A.
43.8
N.A.
44.6
41
43.6
P-Site Identity:
N.A.
6.6
N.A.
13.3
26.6
6.6
P-Site Similarity:
N.A.
20
N.A.
26.6
40
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
6
6
12
6
12
6
17
17
12
12
12
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
6
28
6
0
0
6
6
23
0
28
6
45
12
% D
% Glu:
0
0
0
39
0
6
12
0
62
56
6
39
6
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
6
12
12
0
17
0
0
6
0
6
6
6
12
6
% G
% His:
0
0
6
0
0
6
6
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
6
% I
% Lys:
0
0
6
6
0
6
0
0
0
6
0
0
0
6
12
% K
% Leu:
6
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% M
% Asn:
0
6
0
0
0
0
0
0
0
0
0
0
0
6
0
% N
% Pro:
67
56
6
6
6
0
67
23
0
0
6
0
6
0
6
% P
% Gln:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
6
% Q
% Arg:
12
0
67
0
0
56
12
17
12
0
62
6
6
12
50
% R
% Ser:
6
6
0
0
73
0
0
34
6
0
0
0
6
6
0
% S
% Thr:
0
6
0
6
6
0
0
0
0
0
6
0
6
0
0
% T
% Val:
0
6
0
0
0
0
0
6
6
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _