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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3A
All Species:
33.64
Human Site:
S1256
Identified Species:
43.53
UniProt:
Q14152
Number Species:
17
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14152
NP_003741.1
1382
166569
S1256
R
R
G
P
A
E
E
S
S
S
W
R
D
S
S
Chimpanzee
Pan troglodytes
XP_001153575
1382
166541
S1256
R
R
G
P
A
E
E
S
S
S
W
R
D
S
S
Rhesus Macaque
Macaca mulatta
XP_001102472
1228
147070
S1102
R
R
G
P
A
E
E
S
S
S
W
R
D
S
S
Dog
Lupus familis
XP_852131
1350
163016
S1227
R
R
G
P
A
E
E
S
S
S
W
R
D
S
N
Cat
Felis silvestris
Mouse
Mus musculus
P23116
1344
161918
S1217
R
R
G
P
A
E
E
S
S
S
W
R
D
S
S
Rat
Rattus norvegicus
Q1JU68
1354
163177
S1227
R
R
G
P
A
E
E
S
S
S
W
R
D
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514639
1362
163866
A1241
R
R
G
P
A
E
E
A
S
S
W
R
D
S
N
Chicken
Gallus gallus
XP_421787
1505
177889
T1382
R
R
G
P
A
E
E
T
S
S
W
R
D
S
S
Frog
Xenopus laevis
A2VD00
1424
168482
E1322
D
R
R
P
V
R
E
E
S
A
W
R
R
G
G
Zebra Danio
Brachydanio rerio
Q6PCR7
1267
151273
Q1161
G
G
G
G
G
E
E
Q
S
S
W
R
D
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN25
1140
133861
T1046
R
A
D
G
A
R
R
T
D
E
P
Q
R
E
T
Honey Bee
Apis mellifera
XP_397439
1143
134949
Q1053
R
D
K
S
D
A
I
Q
N
S
P
R
D
L
P
Nematode Worm
Caenorhab. elegans
P34339
1076
124390
T982
P
V
V
S
P
P
K
T
D
A
P
S
V
S
E
Sea Urchin
Strong. purpuratus
XP_798957
1284
149812
S1125
R
G
D
D
S
Q
Q
S
A
R
R
L
E
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XHR2
962
111545
A875
A
Q
P
P
R
E
S
A
A
A
A
A
A
A
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD55
987
114281
P898
A
P
A
A
P
Y
V
P
K
W
K
R
Q
T
T
Baker's Yeast
Sacchar. cerevisiae
P38249
964
110326
A875
S
T
P
Y
S
F
R
A
G
N
R
E
P
P
S
Red Bread Mold
Neurospora crassa
Q7RWT1
1007
114509
T921
A
A
P
P
A
E
R
T
E
A
A
A
P
P
R
Conservation
Percent
Protein Identity:
100
99.9
86.5
94.2
N.A.
93.1
93.1
N.A.
88.2
75.6
72.1
75
N.A.
41.5
42.1
31.4
45.4
Protein Similarity:
100
99.9
87.4
95.9
N.A.
95.5
95.5
N.A.
93.1
81.7
81.4
82.1
N.A.
58
58.5
48.3
62.1
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
93.3
40
60
N.A.
13.3
26.6
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
46.6
60
N.A.
33.3
33.3
26.6
46.6
Percent
Protein Identity:
N.A.
27.2
N.A.
27.1
23.3
28.2
Protein Similarity:
N.A.
43.8
N.A.
44.6
41
43.6
P-Site Identity:
N.A.
13.3
N.A.
6.6
6.6
20
P-Site Similarity:
N.A.
53.3
N.A.
20
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
12
6
6
56
6
0
17
12
23
12
12
6
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
12
6
6
0
0
0
12
0
0
0
56
0
0
% D
% Glu:
0
0
0
0
0
62
56
6
6
6
0
6
6
6
6
% E
% Phe:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
12
50
12
6
0
0
0
6
0
0
0
0
6
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
6
0
0
0
6
0
6
0
6
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
6
0
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
6
6
0
0
0
0
12
% N
% Pro:
6
6
17
62
12
6
0
6
0
0
17
0
12
12
12
% P
% Gln:
0
6
0
0
0
6
6
12
0
0
0
6
6
0
0
% Q
% Arg:
62
50
6
0
6
12
17
0
0
6
12
67
12
6
12
% R
% Ser:
6
0
0
12
12
0
6
39
56
56
0
6
0
56
39
% S
% Thr:
0
6
0
0
0
0
0
23
0
0
0
0
0
6
12
% T
% Val:
0
6
6
0
6
0
6
0
0
0
0
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
6
56
0
0
0
0
% W
% Tyr:
0
0
0
6
0
6
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _