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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3A
All Species:
32.42
Human Site:
S1309
Identified Species:
41.96
UniProt:
Q14152
Number Species:
17
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14152
NP_003741.1
1382
166569
S1309
S
E
R
E
E
V
S
S
W
R
R
A
D
D
R
Chimpanzee
Pan troglodytes
XP_001153575
1382
166541
S1309
S
E
R
E
E
V
S
S
W
R
R
A
D
D
R
Rhesus Macaque
Macaca mulatta
XP_001102472
1228
147070
S1155
S
E
R
E
E
V
S
S
W
R
R
A
D
D
R
Dog
Lupus familis
XP_852131
1350
163016
S1277
S
E
R
E
E
V
S
S
W
R
R
A
D
D
R
Cat
Felis silvestris
Mouse
Mus musculus
P23116
1344
161918
S1273
S
E
R
E
E
A
S
S
W
R
R
T
D
D
R
Rat
Rattus norvegicus
Q1JU68
1354
163177
S1283
S
E
R
E
E
A
S
S
W
R
R
T
D
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514639
1362
163866
S1295
S
E
R
E
E
T
S
S
W
R
R
T
D
E
R
Chicken
Gallus gallus
XP_421787
1505
177889
S1428
S
D
R
E
E
P
S
S
W
R
R
A
D
D
R
Frog
Xenopus laevis
A2VD00
1424
168482
D1353
E
D
R
K
E
P
S
D
V
R
R
A
A
P
K
Zebra Danio
Brachydanio rerio
Q6PCR7
1267
151273
S1206
R
D
Q
D
E
G
G
S
W
R
R
G
G
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN25
1140
133861
V1079
A
E
R
R
D
R
D
V
R
E
T
R
G
D
Q
Honey Bee
Apis mellifera
XP_397439
1143
134949
R1083
S
K
H
D
E
R
K
R
P
P
E
D
D
G
P
Nematode Worm
Caenorhab. elegans
P34339
1076
124390
G1011
R
N
R
Q
G
G
G
G
A
G
G
S
E
E
Q
Sea Urchin
Strong. purpuratus
XP_798957
1284
149812
P1221
N
D
D
R
G
S
R
P
E
P
R
G
E
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XHR2
962
111545
I904
R
G
G
D
S
S
S
I
P
S
G
S
R
D
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD55
987
114281
P927
R
R
S
N
R
G
P
P
P
G
D
D
H
W
G
Baker's Yeast
Sacchar. cerevisiae
P38249
964
110326
Q904
A
K
L
D
M
I
A
Q
K
Q
R
E
M
E
E
Red Bread Mold
Neurospora crassa
Q7RWT1
1007
114509
G950
A
A
K
A
A
S
G
G
G
N
A
A
A
V
P
Conservation
Percent
Protein Identity:
100
99.9
86.5
94.2
N.A.
93.1
93.1
N.A.
88.2
75.6
72.1
75
N.A.
41.5
42.1
31.4
45.4
Protein Similarity:
100
99.9
87.4
95.9
N.A.
95.5
95.5
N.A.
93.1
81.7
81.4
82.1
N.A.
58
58.5
48.3
62.1
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
80
86.6
40
33.3
N.A.
20
20
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
86.6
93.3
60
60
N.A.
40
33.3
40
33.3
Percent
Protein Identity:
N.A.
27.2
N.A.
27.1
23.3
28.2
Protein Similarity:
N.A.
43.8
N.A.
44.6
41
43.6
P-Site Identity:
N.A.
13.3
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
26.6
N.A.
0
53.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
6
0
6
6
12
6
0
6
0
6
39
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
23
6
23
6
0
6
6
0
0
6
12
50
50
0
% D
% Glu:
6
45
0
45
62
0
0
0
6
6
6
6
12
23
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
6
6
0
12
17
17
12
6
12
12
12
12
6
6
% G
% His:
0
0
6
0
0
0
0
0
0
0
0
0
6
0
0
% H
% Ile:
0
0
0
0
0
6
0
6
0
0
0
0
0
0
0
% I
% Lys:
0
12
6
6
0
0
6
0
6
0
0
0
0
0
6
% K
% Leu:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
6
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
6
6
0
6
0
0
0
0
0
6
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
12
6
12
17
12
0
0
0
12
12
% P
% Gln:
0
0
6
6
0
0
0
6
0
6
0
0
0
0
12
% Q
% Arg:
23
6
62
12
6
12
6
6
6
56
67
6
6
0
50
% R
% Ser:
50
0
6
0
6
17
56
50
0
6
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
6
0
0
0
0
6
17
0
0
0
% T
% Val:
0
0
0
0
0
23
0
6
6
0
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
50
0
0
0
0
6
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _