KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3A
All Species:
36.06
Human Site:
S1355
Identified Species:
46.67
UniProt:
Q14152
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.12
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14152
NP_003741.1
1382
166569
S1355
E
G
E
K
E
K
A
S
W
R
A
E
K
D
R
Chimpanzee
Pan troglodytes
XP_001153575
1382
166541
S1355
E
G
E
K
E
K
A
S
W
R
A
E
K
D
R
Rhesus Macaque
Macaca mulatta
XP_001102472
1228
147070
S1201
E
G
E
K
E
K
A
S
W
R
A
E
K
D
R
Dog
Lupus familis
XP_852131
1350
163016
S1323
E
G
E
K
E
K
A
S
W
R
A
E
K
D
R
Cat
Felis silvestris
Mouse
Mus musculus
P23116
1344
161918
S1317
E
G
E
K
E
K
A
S
W
R
A
E
K
D
R
Rat
Rattus norvegicus
Q1JU68
1354
163177
S1327
E
G
E
K
E
K
A
S
W
R
A
E
K
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514639
1362
163866
S1335
D
G
E
K
E
R
G
S
W
R
S
E
K
E
R
Chicken
Gallus gallus
XP_421787
1505
177889
S1478
D
G
E
K
E
K
G
S
W
K
T
E
K
E
R
Frog
Xenopus laevis
A2VD00
1424
168482
R1397
D
R
E
K
P
S
W
R
T
E
K
K
E
E
K
Zebra Danio
Brachydanio rerio
Q6PCR7
1267
151273
T1240
R
D
S
G
E
K
S
T
W
R
S
D
K
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN25
1140
133861
E1112
T
A
P
A
T
R
E
E
K
P
A
A
K
R
D
Honey Bee
Apis mellifera
XP_397439
1143
134949
S1114
S
T
V
L
C
T
I
S
F
L
S
E
Y
T
N
Nematode Worm
Caenorhab. elegans
P34339
1076
124390
L1050
P
P
T
G
R
N
S
L
P
R
R
D
G
P
P
Sea Urchin
Strong. purpuratus
XP_798957
1284
149812
G1256
P
T
W
R
G
Q
G
G
E
K
G
G
E
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XHR2
962
111545
R935
R
L
D
A
P
S
S
R
Q
D
T
D
R
W
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD55
987
114281
A957
R
E
R
S
G
P
P
A
E
G
G
D
R
W
G
Baker's Yeast
Sacchar. cerevisiae
P38249
964
110326
T938
A
T
P
A
T
P
A
T
P
T
P
S
S
G
P
Red Bread Mold
Neurospora crassa
Q7RWT1
1007
114509
R981
S
G
R
P
E
N
D
R
D
V
P
P
A
E
P
Conservation
Percent
Protein Identity:
100
99.9
86.5
94.2
N.A.
93.1
93.1
N.A.
88.2
75.6
72.1
75
N.A.
41.5
42.1
31.4
45.4
Protein Similarity:
100
99.9
87.4
95.9
N.A.
95.5
95.5
N.A.
93.1
81.7
81.4
82.1
N.A.
58
58.5
48.3
62.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
66.6
66.6
13.3
40
N.A.
13.3
13.3
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
46.6
73.3
N.A.
20
26.6
20
26.6
Percent
Protein Identity:
N.A.
27.2
N.A.
27.1
23.3
28.2
Protein Similarity:
N.A.
43.8
N.A.
44.6
41
43.6
P-Site Identity:
N.A.
6.6
N.A.
0
6.6
13.3
P-Site Similarity:
N.A.
33.3
N.A.
20
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
17
0
0
39
6
0
0
39
6
6
0
0
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
6
6
0
0
0
6
0
6
6
0
23
0
39
6
% D
% Glu:
34
6
50
0
56
0
6
6
12
6
0
50
12
23
0
% E
% Phe:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% F
% Gly:
0
50
0
12
12
0
17
6
0
6
12
6
6
6
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
50
0
45
0
0
6
12
6
6
56
0
12
% K
% Leu:
0
6
0
6
0
0
0
6
0
6
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
6
% N
% Pro:
12
6
12
6
12
12
6
0
12
6
12
6
0
6
17
% P
% Gln:
0
0
0
0
0
6
0
0
6
0
0
0
0
0
0
% Q
% Arg:
17
6
12
6
6
12
0
17
0
50
6
0
12
12
50
% R
% Ser:
12
0
6
6
0
12
17
50
0
0
17
6
6
0
0
% S
% Thr:
6
17
6
0
12
6
0
12
6
6
12
0
0
6
0
% T
% Val:
0
0
6
0
0
0
0
0
0
6
0
0
0
0
0
% V
% Trp:
0
0
6
0
0
0
6
0
50
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _